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Table 1 Preoperative characteristics of 44 patients with Graves’ orbitopathy and dysthyroid optic neuropathy

From: Preoperative clinical factors and visual outcomes following orbital decompression with dysthyroid optic neuropathy

Parameter

Total

Without surgery

Urgent surgery

P

Number of patients (male/female)

44 (15/29)

27 (9/18)

17 (6/11)

0.014*

Age, years

53.4 ± 8.9

47.1 ± 6.7

59.7 ± 13.2

< 0.01*

Disease duration, months

4.8 ± 5.0

3.1 ± 6.6

6.5 ± 4.1

< 0.01*

Laterality of GO

 Bilateral

26

19

7

< 0.0

 Unilateral

18

8

10

1*

 Number of treatments with pulsed steroid therapy

2.6 ± 2.1

3.2 ± 1.1

2.1 ± 1.3

< 0.01*

Orbital radiation therapy

 +

24

16

8

< 0.01

 -

20

11

9

*

Thyroid function

 Stable

32

20

12

0.013

 Unstable

12

7

5

*

 TRAb IU/l

16.9 ± 25.7

20

11.4 ± 15.4

11

43.9 ± 44.2

9

0.04*

NA

 Visual acuity, logMAR conversion

0.15 ± 0.33

   

 Better

0.71 ± 0.71

0.12 ± 0.46

0.19 ± 0.27

< 0.01

 Worse

 

0.66 ± 0.55

0.84 ± 0.79

*

Diplopia, central 30 degrees

 +

17

11

6

< 0.01

 -

22

16

9

*

 NA

2

 

2

 

 Asymmetry of proptosis, mm

1.4 ± 1.3

1.3 ± 1.5

1.4 ± 0.8

0.26

 Exophalmos degree

17.8 ± 1.8

18.1 ± 1.9

17.2 ± 1.2

0.06

Secondary high IOP

 +

8

4

4

0.15

 -

23

11

12

 

 NA

13

10

3

 

Corneal problems

 +

16

8

8

 

 -

15

9

6

0.22

 NA

13

10

3

 

Psychological history

 +

9

6

3

0.39

 -

35

21

14

 

Smoking history

 +

10

6

4

 

 -

27

14

13

0.29

 NA

7

7

0

 
  1. A t-test was used to analyze the data on smoking, while diplopia data were analyzed with the χ2 test. These data are expressed as mean ± standard deviation
  2. TRAb: Thyrotrophin receptor antibody