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Table 1 Clinical characteristics and main optical coherence tomography parameters of the glaucoma patients and the healthy subjects

From: Diagnostic capability of a linear discriminant function applied to a novel Spectralis OCT glaucoma-detection protocol

 Teaching Set (n = 68)Validating Set (n = 68)
Healthy Subjects (n = 34)Glaucoma Group (n = 34)Healthy Subjects (n = 34)Glaucoma Group (n = 34)
Mean ± SDMean ± SDP*Mean ± SDMean ± SDP*
Age (years)62.85 ± 8.2565.32 ± 10.480.05562.32 ± 8.6864.20 ± 9.720.062
Sex (men:women)20:1418:160.32415:1917:170.216
BCVA (Snellen)0.96 ± 0.080.93 ± 0.130.4690.97 ± 0.060.91 ± 0.080.010
IOP (mm Hg)17.46 ± 3.1016.89 ± 0.4930.49317.33 ± 2.9617.30 ± 3.320.967
MD (dB)−0.34 ± 1.45−2.85 ± 1.97<  0.001− 0.26 ± 1.47−2.78 ± 1.71<  0.001
Spherical Equivalent (D)0.93 ± 1.570.35 ± 2.390.1900.82 ± 1.690.17 ± 2.240.219
CCP (μm)558.01 ± 41.25535.14 ± 37.320.072556.33 ± 42.31550.33 ± 34.550.540
pRNFL glaucoma global (μm)97.96 ± 8.5880.93 ± 13.94<  0.00196.44 ± 9.2176.67 ± 13.88<  0.001
BMO–MRW area (mm2)1.99 ± 0.311.96 ± 0.360.7221.98 ± 0.321.95 ± 0.390.813
BMO–MRW global (μm)313.03 ± 54.87236.94 ± 73.65<  0.001314.81 ± 56.12227.93 ± 63.85<  0.001
pRNFL 3.5 global (μm)96.93 ± 7.2783.65 ± 15.65<  0.00197.89 ± 8.2378.79 ± 15.71<  0.001
pRNFL 4.1 global (μm)83.76 ± 5.8871.10 ± 12.92<  0.00184.11 ± 7.5868.71 ± 14.33<  0.001
pRNFL 4.7 global (μm)73.25 ± 5.3663.75 ± 12.25<  0.00173.74 ± 6.6060.86 ± 11.90<  0.001
  1. P*: level of statistical significance in comparison between groups using the t–test (except for gender, Chi-square). Bold text indicates statistically significant results with Bonferroni correction (p <  0.004)
  2. SD Standard deviation, BCVA Best-corrected visual acuity, IOP Intraocular pressure, MD Mean deviation (visual field), dB decibels, D Dioptres, CCP Central corneal pachymetry, pRNFL peripapillary retinal nerve fibre layer, BMO–MRW Bruch membrane opening–minimum rim width