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Table 1 Clinical characteristics and main optical coherence tomography parameters of the glaucoma patients and the healthy subjects

From: Diagnostic capability of a linear discriminant function applied to a novel Spectralis OCT glaucoma-detection protocol

 

Teaching Set (n = 68)

Validating Set (n = 68)

Healthy Subjects (n = 34)

Glaucoma Group (n = 34)

Healthy Subjects (n = 34)

Glaucoma Group (n = 34)

Mean ± SD

Mean ± SD

P*

Mean ± SD

Mean ± SD

P*

Age (years)

62.85 ± 8.25

65.32 ± 10.48

0.055

62.32 ± 8.68

64.20 ± 9.72

0.062

Sex (men:women)

20:14

18:16

0.324

15:19

17:17

0.216

BCVA (Snellen)

0.96 ± 0.08

0.93 ± 0.13

0.469

0.97 ± 0.06

0.91 ± 0.08

0.010

IOP (mm Hg)

17.46 ± 3.10

16.89 ± 0.493

0.493

17.33 ± 2.96

17.30 ± 3.32

0.967

MD (dB)

−0.34 ± 1.45

−2.85 ± 1.97

<  0.001

− 0.26 ± 1.47

−2.78 ± 1.71

<  0.001

Spherical Equivalent (D)

0.93 ± 1.57

0.35 ± 2.39

0.190

0.82 ± 1.69

0.17 ± 2.24

0.219

CCP (μm)

558.01 ± 41.25

535.14 ± 37.32

0.072

556.33 ± 42.31

550.33 ± 34.55

0.540

pRNFL glaucoma global (μm)

97.96 ± 8.58

80.93 ± 13.94

<  0.001

96.44 ± 9.21

76.67 ± 13.88

<  0.001

BMO–MRW area (mm2)

1.99 ± 0.31

1.96 ± 0.36

0.722

1.98 ± 0.32

1.95 ± 0.39

0.813

BMO–MRW global (μm)

313.03 ± 54.87

236.94 ± 73.65

<  0.001

314.81 ± 56.12

227.93 ± 63.85

<  0.001

pRNFL 3.5 global (μm)

96.93 ± 7.27

83.65 ± 15.65

<  0.001

97.89 ± 8.23

78.79 ± 15.71

<  0.001

pRNFL 4.1 global (μm)

83.76 ± 5.88

71.10 ± 12.92

<  0.001

84.11 ± 7.58

68.71 ± 14.33

<  0.001

pRNFL 4.7 global (μm)

73.25 ± 5.36

63.75 ± 12.25

<  0.001

73.74 ± 6.60

60.86 ± 11.90

<  0.001

  1. P*: level of statistical significance in comparison between groups using the t–test (except for gender, Chi-square). Bold text indicates statistically significant results with Bonferroni correction (p <  0.004)
  2. SD Standard deviation, BCVA Best-corrected visual acuity, IOP Intraocular pressure, MD Mean deviation (visual field), dB decibels, D Dioptres, CCP Central corneal pachymetry, pRNFL peripapillary retinal nerve fibre layer, BMO–MRW Bruch membrane opening–minimum rim width