Fig. 1

The effect of Alda-1 intervention on retinal function in N-methyl-N-nitrosourea (MNU)-induced retinitis pigmentosa (RP) rats. a, b Representative waveforms and plots of the b-wave amplitudes in Dark-adapted and Light-adapted 3.0 Electroretinogram (ERG) of rats in all groups. Compared with those of the normal (N) group, the amplitude of ERG, both the Dark-adapted and Light-adapted ERG, in rats of the model (M) group decreased gradually on 1 day and 3days (D1 and D3) after MNU injection, with the ERG waveforms extinguished on D3. The amplitudes in rats in the Alda-1 intervention (A) group also decreased gradually but were significantly higher than those in rats in the M group at each time point (P < 0.05). N: the normal group; M: the model group; A: the Alda-1 intervention group. *, **: P < 0.05, P < 0.01 vs. the N group; #, ##: P < 0.05, P < 0.01 vs. the M group