Variable | Fixed combination (N = 309) | Unfixed combination (N = 329) | ||
---|---|---|---|---|
n | Percentage or mean ± SD | n | Percentage or mean ± SD | |
Sex, male | 170 | 55.0 | 188 | 57.1 |
Age (years) | 309 | 56.5 ± 10.2 | 329 | 57.1 ± 10.2 |
Body weight (kg) | 210 | 61.8 ± 12.5 | 219 | 61.6 ± 11.0 |
Height (cm) | 218 | 163.9 ± 9.2 | 226 | 164.4 ± 8.9 |
Body mass index (kg/m2) | 210 | 22.9 ± 3.5 | 219 | 22.7 ± 3.1 |
Smoking | ||||
 Yes | 33 | 10.7 | 32 | 9.7 |
 No | 178 | 57.6 | 193 | 58.7 |
Medication for other indications | ||||
 Yes | 63 | 20.4 | 74 | 22.5 |
 No | 146 | 47.2 | 149 | 45.3 |
Fasting blood glucose (mg/dL) | 200 | 97.0 ± 17.4 | 213 | 97.8 ± 15.4 |
HbA1c (NGSP) (%) | 205 | 5.6 ± 0.6 | 216 | 5.6 ± 0.5 |
Urine glucose | ||||
 Negative (−) | 208 | 67.3 | 221 | 67.2 |
 Positive (≥±) | 4 | 1.3 | 2 | 0.6 |
Urine protein | ||||
 Negative (−) | 192 | 62.1 | 207 | 62.9 |
 Positive (≥±) | 24 | 7.8 | 19 | 5.8 |
Antihypertensive drug | ||||
 Yes | 46 | 14.9 | 52 | 15.8 |
 No | 163 | 52.8 | 171 | 52.0 |
Systolic blood pressure (mm Hg) | 218 | 119.9 ± 15.5 | 226 | 120.3 ± 16.2 |
Diastolic blood pressure (mm Hg) | 218 | 74.5 ± 11.3 | 226 | 75.6 ± 11.2 |
Total cholesterol (mg/dL) | 64 | 207.3 ± 32.0 | 53 | 201.7 ± 35.9 |
Triglycerides (mg/dL) | 217 | 107.9 ± 64.8 | 226 | 101.3 ± 66.6 |
HDL cholesterol (mg/dL) | 217 | 64.6 ± 16.7 | 226 | 65.0 ± 16.9 |
LDL cholesterol (mg/dL) | 217 | 124.4 ± 26.9 | 226 | 126.2 ± 31.2 |
Aspartate transaminase (U/L) | 217 | 23.7 ± 9.3 | 226 | 23.0 ± 8.8 |
Alanine aminotransferase (U/L) | 217 | 23.3 ± 14.6 | 226 | 23.5 ± 13.6 |
γ-GTP (U/L) | 216 | 41.4 ± 49.1 | 226 | 37.6 ± 41.6 |
Common comorbidities | ||||
 Hypertension | 92 | 29.8 | 110 | 33.4 |
 Cancer | 90 | 29.1 | 114 | 34.7 |
 Hyperlipidemia | 87 | 28.2 | 111 | 33.7 |
 Diabetes mellitus | 85 | 27.5 | 97 | 29.5 |
 Insomnia | 44 | 14.2 | 44 | 13.4 |
 Liver disorder | 43 | 13.9 | 44 | 13.4 |
 Asthma or COPD | 41 | 13.3 | 66 | 20.1 |
 Gastrointestinal ulcer | 38 | 12.3 | 41 | 12.5 |
 Atherosclerosis or PAOD | 31 | 10.0 | 38 | 11.6 |
 Anemia | 30 | 9.7 | 33 | 10.0 |
 Coronary artery disease | 26 | 8.4 | 33 | 10.0 |
 Heart failure | 22 | 7.1 | 35 | 10.6 |
Locations | ||||
 8 regions | ||||
  Hokkaido | 7 | 2.3 | 3 | 0.9 |
  Tohoku | 14 | 4.5 | 6 | 1.8 |
  Kanto | 176 | 57.0 | 207 | 62.9 |
  Chubu | 38 | 12.3 | 37 | 11.2 |
  Kinki | 38 | 12.3 | 36 | 10.9 |
  Chugoku | 10 | 3.2 | 9 | 2.7 |
  Shikoku | 2 | 0.6 | 2 | 0.6 |
  Kyushu | 24 | 7.8 | 29 | 8.8 |
 Areas | ||||
  East Japan | 210 | 68.0 | 220 | 66.9 |
  West Japan | 99 | 32.0 | 109 | 33.1 |
 City size | ||||
  Tokyo and all GODMCs | 255 | 82.5 | 289 | 87.8 |
  Other than GODMCs | 54 | 17.5 | 40 | 12.2 |