Skip to main content

Table 3 Adherence to fixed- and unfixed-combination therapies with latanoprost and timolol during the 12-month post-index period

From: Comparison of adherence between fixed and unfixed topical combination glaucoma therapies using Japanese healthcare/pharmacy claims database: a retrospective non-interventional cohort study

 

All patients

N = 162

Fixed combination

N = 123

Unfixed combination

N = 39

 

PDC, mean ± SD (%)

78.9 ± 33.7

82.9 ± 31.1

66.5 ± 38.6

P = 0.0191a

 

n (%)

n (%)

n (%)

 

80 + % PDC

114 (70.4)

93 (75.6)

21 (53.8)

P = 0.0095b

< 80% PDC

48 (29.6)

30 (24.4)

18 (46.2)

 

60–79% PDC

8 (4.9)

6 (4.9)

2 (5.1)

 

40–59% PDC

9 (5.6)

5 (4.1)

4 (10.3)

 

20–39% PDC

10 (6.2)

7 (5.7)

3 (7.7)

 

< 20% PDC

21 (13.0)

12 (9.8)

9 (23.1)

 
  1. PDC proportion of days covered
  2. a, t-test (fixed vs. unfixed); b, χ2 test (fixed vs. unfixed). Note: a p-value < 0.05 / 9 (= 0.00556) was considered statistically significant (by Bonferroni correction)