| All patients N = 162 | Fixed combination N = 123 | Unfixed combination N = 39 |  |
---|---|---|---|---|
PDC, mean ± SD (%) | 78.9 ± 33.7 | 82.9 ± 31.1 | 66.5 ± 38.6 | P = 0.0191a |
 | n (%) | n (%) | n (%) |  |
80 + % PDC | 114 (70.4) | 93 (75.6) | 21 (53.8) | P = 0.0095b |
< 80% PDC | 48 (29.6) | 30 (24.4) | 18 (46.2) |  |
60–79% PDC | 8 (4.9) | 6 (4.9) | 2 (5.1) |  |
40–59% PDC | 9 (5.6) | 5 (4.1) | 4 (10.3) |  |
20–39% PDC | 10 (6.2) | 7 (5.7) | 3 (7.7) |  |
< 20% PDC | 21 (13.0) | 12 (9.8) | 9 (23.1) |  |