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Table 3 Adherence to fixed- and unfixed-combination therapies with latanoprost and timolol during the 12-month post-index period

From: Comparison of adherence between fixed and unfixed topical combination glaucoma therapies using Japanese healthcare/pharmacy claims database: a retrospective non-interventional cohort study

  All patients
N = 162
Fixed combination
N = 123
Unfixed combination
N = 39
 
PDC, mean ± SD (%) 78.9 ± 33.7 82.9 ± 31.1 66.5 ± 38.6 P = 0.0191a
  n (%) n (%) n (%)  
80 + % PDC 114 (70.4) 93 (75.6) 21 (53.8) P = 0.0095b
< 80% PDC 48 (29.6) 30 (24.4) 18 (46.2)  
60–79% PDC 8 (4.9) 6 (4.9) 2 (5.1)  
40–59% PDC 9 (5.6) 5 (4.1) 4 (10.3)  
20–39% PDC 10 (6.2) 7 (5.7) 3 (7.7)  
< 20% PDC 21 (13.0) 12 (9.8) 9 (23.1)  
  1. PDC proportion of days covered
  2. a, t-test (fixed vs. unfixed); b, χ2 test (fixed vs. unfixed). Note: a p-value < 0.05 / 9 (= 0.00556) was considered statistically significant (by Bonferroni correction)
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