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Table 4 Comparison of adherences to fixed-combination therapies during the 12-month post-index period

From: Comparison of adherence between fixed and unfixed topical combination glaucoma therapies using Japanese healthcare/pharmacy claims database: a retrospective non-interventional cohort study

 

PG/BB

N = 241

CAI/BB

N = 68

 

PDC, mean ± SD (%)

81.2 ± 31.0

71.6 ± 34.9

P = 0.0438a

 

n (%)

n (%)

 

80 + % PDC

176 (73.0)

39 (57.4)

P = 0.0131b

< 80% PDC

65 (27.0)

29 (42.6)

 

60–79% PDC

12 (5.0)

4 (5.9)

 

40–59% PDC

15 (6.2)

9 (13.2)

 

20–39% PDC

13 (5.4)

6 (8.8)

 

< 20% PDC

25 (10.4)

10 (14.7)

 
  1. PDC proportion of days covered, PG prostaglandin analogs, BB β-blockers, CAI carbonic anhydrase inhibitors
  2. a, t-test (PG/BB vs. CAI/BB); b, χ2 test (PG/BB vs. CAI/BB). Note: a p-value < 0.05 / 9 (= 0.00556) was considered statistically significant (by Bonferroni correction)