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Table 4 Comparison of adherences to fixed-combination therapies during the 12-month post-index period

From: Comparison of adherence between fixed and unfixed topical combination glaucoma therapies using Japanese healthcare/pharmacy claims database: a retrospective non-interventional cohort study

  PG/BB
N = 241
CAI/BB
N = 68
 
PDC, mean ± SD (%) 81.2 ± 31.0 71.6 ± 34.9 P = 0.0438a
  n (%) n (%)  
80 + % PDC 176 (73.0) 39 (57.4) P = 0.0131b
< 80% PDC 65 (27.0) 29 (42.6)  
60–79% PDC 12 (5.0) 4 (5.9)  
40–59% PDC 15 (6.2) 9 (13.2)  
20–39% PDC 13 (5.4) 6 (8.8)  
< 20% PDC 25 (10.4) 10 (14.7)  
  1. PDC proportion of days covered, PG prostaglandin analogs, BB β-blockers, CAI carbonic anhydrase inhibitors
  2. a, t-test (PG/BB vs. CAI/BB); b, χ2 test (PG/BB vs. CAI/BB). Note: a p-value < 0.05 / 9 (= 0.00556) was considered statistically significant (by Bonferroni correction)
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