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Table 2 Vascular density in superficial capillary network (SCN) of normal subjects and subtypes of diabetic retinopathy (N = 188)

From: Quantitative assessment of vascular density in diabetic retinopathy subtypes with optical coherence tomography angiography

Groups

VD/

Reference group

NL (40 eyes)

Median (range)

(%)

NDR (39eyes)

Median (range)

(%)

NPDR (64eyes)

Median (range)

(%)

PDR (45eyes)

Median (range)

(%)

P-value

Kruskal –Wallis test

Whole image

Normal

NDR

NPDR

54.65

(47.00–50.04)

51.90

(42.40–56.28)

< 0.001*

48.05

(35.07–55.78)

< 0.001*

< 0.001*

45.50

(33.74–50.48)

< 0.001*

< 0.001*

< 0.001*

< 0.001

Fovea

Normal

NDR

NPDR

29.17

(23.94–41.86)

26.26

(20.77–34.20)

0.013*

27.07

(16.11–38.10)

0.033*

0.859*

24.00

(17.68–36.14)

< 0.001*

0.045*

0.062*

0.001

Para-fovea

Normal

NDR

NPDR

57.37

(50.09–62.24)

54.54

(42.74–59.47)

< 0.001*

49.96

(36.69–57.81)

< 0.001*

< 0.001*

47.24

(35.77–52.32)

< 0.001*

< 0.001*

< 0.001*

< 0.001

Superior-hemi

Normal

NDR

NPDR

57.25

(48.60–62.67)

54.03

(44.06–59.20)

< 0.001*

49.92

(34.64–57.05)

< 0.001*

< 0.001*

46.67

(33.59–53.64)

< 0.001*

< 0.001*

< 0.001*

< 0.001

Inferior-hemi

Normal

NDR

NPDR

57.39

(49.50–62.60)

54.13

(41.44–59.73)

< 0.001*

49.70

(38.70–58.55)

< 0.001*

< 0.001*

46.82

(38.06–53.41)

< 0.001*

< 0.001*

< 0.001*

< 0.001

Temporal

Normal

NDR

NPDR

55.76

(48.17–60.28)

53.57

(39.58–58.12)

0.001*

48.62

(36.52–57.70)

< 0.001*

< 0.001*

46.17

(37.79–52.46)

< 0.001*

< 0.001*

< 0.001*

< 0.001

Superior

Normal

NDR

NPDR

58.50

(49.62–63.98)

55.57

(45.22–59.62)

< 0.001*

50.58

(36.96–57.50)

< 0.001*

< 0.001*

46.25

(34.26–53.65)

< 0.001*

< 0.001*

0.001*

< 0.001

Nasal

Normal

NDR

NPDR

57.13

(49.50–62.64)

53.44

(44.22–58.51)

< 0.001*

49.31

(33.37–57.84)

< 0.001*

0.001*

46.34

(31.09–52.93)

< 0.001*

< 0.001*

0.002*

< 0.001

Inferior

Normal

NDR

NPDR

57.87

(48.20–63.75)

55.06

(42.01–61.70)

< 0.001*

50.35

(39.90–59.36)

< 0.001*

< 0.001*

47.34

(38.26–54.97)

< 0.001*

< 0.001*

< 0.001*

0.043

  1. NDR No diabetic retinopathy, NL Normal, NPDR Nonproliferative diabetic retinopathy, PDR Proliferative diabetic retinopathy
  2. * Mann- Whitney test