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Table 3 Vascular density in deep capillary network (DCN) in normal subjects and subtypes of diabetic retinopathy (N = 188)

From: Quantitative assessment of vascular density in diabetic retinopathy subtypes with optical coherence tomography angiography

Groups

VD/

Reference group

NL (40 eyes)

Median (range)

(%)

NDR (39eyes)

Median (range)

(%)

NPDR (64eyes)

Median (range)

(%)

PDR (33eyes)

Median (range)

(%)

P-value

Kruskal –Wallis test

Whole image

Normal

NDR

NPDR

60.42

(47.00–64.55)

58.05

(51.34–60.64)

< 0.001*

53.84

(41.34–60.67)

< 0.001*

< 0.001*

51.24

(42.50–57.58)

< 0.001*

< 0.001*

< 0.001*

< 0.001

Fovea

Normal

NDR

NPDR

31.24

(20.30–42.32)

27.72

(20.28–35.46)

0.001*

27.14

(15.48–40.50)

< 0.001*

0.225

24.94

(12.19–39.30)

< 0.001*

0.050*

0.362*

< 0.001

Para-fovea

Normal

NDR

NPDR

62.89

(50.10–67.22)

60.77

(52.90–63.51)

< 0.001*

56.49

(42.94–62.75)

< 0.001*

< 0.001*

54.16

(42.88–59.89)

< 0.001*

< 0.001*

0.001*

< 0.001

Superior hemi

Normal

NDR

NPDR

63.45

(50.80–67.76)

61.02

(52.40–64.34)

< 0.001*

56.14

(44.02–62.61)

< 0.001*

< 0.001*

55.33

(41.19–61.91)

< 0.001*

< 0.001*

0.026*

< 0.001

Inferior hemi

Normal

NDR

NPDR

62.91

(49.50–66.68)

60.51

(52.17–63.94)

< 0.001*

55.96

(40.75–63.36)

< 0.001*

0.001*

54.07

(43.65–60.35)

< 0.001*

< 0.001*

< 0.001*

< 0.001

Temporal

Normal

NDR

NPDR

61.49

(48.50–64.82)

61.04

(49.90–63.36)

0.011*

53.33

(32.32–61.74)

< 0.001*

< 0.001*

53.31

(42.70–60.56)

< 0.001*

< 0.001*

0.004*

< 0.001

Superior

Normal

NDR

NPDR

64.82

(51.20–69.15)

62.09

(53.30–65.34)

< 0.001*

58.62

(45.35–63.41)

< 0.001*

< 0.001*

55.60

(42.14–60.70)

< 0.001*

< 0.001*

0.005*

< 0.001

Nasal

Normal

NDR

NPDR

62.56

(52.90–67.02)

59.17

(52.40–62.53)

< 0.001*

55.64

(35.39–63.44)

< 0.001*

0.001*

53.48

(39.92–59.70)

< 0.001*

< 0.001*

0.020*

< 0.001

Inferior

Normal

NDR

NPDR

63.76

(48.20–67.86)

62.09

(52.23–65.59)

< 0.001*

56.76

(43.45–64.21)

< 0.001*

0.013*

54.06

(44.73–61.92)

< 0.001*

< 0.001*

< 0.001*

< 0.001

  1. NDR: No diabetic retinopathy, NL: Normal, NPDR: Nonproliferative diabetic retinopathy, PDR: Proliferative diabetic retinopathy
  2. *Mann- Whitney test