Table 2 List of predicted TF gene biomarkers in TED
From: A data-driven approach for the discovery of biomarkers associated with thyroid eye disease
S.No. | Gene names | Fold-change | Regulation type | Disease ontology term | KEGG pathway disease term | GO biological process term |
|---|---|---|---|---|---|---|
1. | EGR1 | 3.0166 | Up | autoimmune disease | Autoimmune thyroid disease (hsa05320), Thyroid hormone signaling pathway (hsa04919) | immune response |
2. | FOS | 3.0109 | Up | autoimmune disease, thyroid gland disease | Autoimmune thyroid disease (hsa05320), Thyroid hormone signaling pathway (hsa04919) | innate immune response, immune response |
3. | MAF | 2.4210 | Up | -- | Autoimmune thyroid disease (hsa05320), | regulation of immune response, immune response |
4. | NR4A1 | 2.0338 | Up | Thyroid carcinoma, Diabetic Retinopathy, autoimmune disease | – | – |