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Table 5 AUCs and sensitivities to distinguish early-stage POAG from healthy subjects and comparison between different parameters using DeLong test

From: Diagnostic capability of different morphological parameters for primary open‐angle glaucoma in the Chinese population

ROC AUC 95 % confidence intervals) Sentivity at 90 % specificity Sentivity at 95 % specificity
Global RNFL 0.933 (0.897,0.969) 82.2 71.2
Global BMO-MRW 0.907 (0.859,0.954) 76.7 57.5
Global BMO-MRA 0.859 (0.801,0.917) 65.8 46.6
Global rim area 0.69 (0.605,0.775) 37 30.1
DeLong- test for AUCs
  AUC1   AUC2 p
Global BMO-MRW 0.907 Global BMO-MRA 0.859 0.03
Global BMO-MRW 0.907 Global RNFL 0.933 0.29
Global BMO-MRW 0.907 Total rim area 0.69 < 0.001
Global BMO-MRA 0.859 Global RNFL 0.933 0.004
Global BMO-MRA 0.859 Total rim area 0.69 < 0.001
Global RNFL 0.933 Total rim area 0.69 < 0.001
  1. The results were considered statistically significant when p < 0.008
  2. AUC area under the curve, POAG primary open-angle glaucoma, BMO-MRW Bruch;s membrane opening-minimum rim width, BMO-MRA Bruch’s membrane opening-minimum rim area, RNFL retinal nerve fiber layer
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BMC Ophthalmology

ISSN: 1471-2415

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