Fig. 2
From: RNA sequencing and bioinformatics analysis of human lens epithelial cells in age-related cataract
Differentially expressed genes (DEGs) in anterior capsule tissues between the two groups. a The number of differentially expressed genes (DEGs) in the JBZ group and ZCR group (P < 0.05, Fold change (FC) > 2). The red histogram represented upregulated gens and a blue histogram represented downregulated gens. b The MA plots visualizing the DEGs between the two groups. The X-axis represented the average expression of all samples for comparison after normalization; the Y-axis represented log2FoldChange. The red dots above the red line represented the up-regulated DEGs, and the red dots below the red line represented the down-regulated DEGs. c The volcano plot of the DEGs between two groups. Red dots represented significantly up-regulated differential genes, green dots represented significantly down-regulated differential genes, and gray dots represented non-significantly differential genes. d Heat-maps of hierarchical clustering analysis of DEGs between two groups. The horizontal ordinate represents the clustering of samples from the JBZ and ZCR groups. The longitudinal coordinates represent the DEGs and the clustering of genes. The red color indicates up-regulated genes, while the blue color indicates down-regulated genes