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Fig. 5 | BMC Ophthalmology

Fig. 5

From: Targeted next generation sequencing and family survey enable correct genetic diagnosis in CRX associated macular dystrophy – a case report

Fig. 5

Imaging of proband’s father (I/2) Images (a to d) at age 73 (asymptomatic. Colour images of both maculae which appeared normal (a and b). Autofluorescence (AF) revealed central patchy reduction in AF signal, consistent with early atrophy (c and d). Images E to J of I:2 9 years later. Optos imaging showing distinct macular atrophy in both eyes and a choroidal naevus at left superotemporal arcade (e and f). AF imaging showing further atrophy at the central macula with central foveal sparing (g and h). Optical coherence tomography (OCT) showing preservation of the ellipsoid zone in the foveal area demarcated by red arrows, and the extent of loss of the ellipsoid zone denoted by yellow arrows (i and j)

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BMC Ophthalmology

ISSN: 1471-2415

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