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Table 1 Clinical signs and subjective symptoms before and after eyelid debris debridement and meibomian gland expression in patients with moderate and severe meibomian gland dysfunction

From: Effects of lid debris debridement combined with meibomian gland expression on the ocular surface MMP-9 levels and clinical outcomes in moderate and severe meibomian gland dysfunction

Parameters Before treatment 4 weeks after the treatment P value
TBUT (sec)a 4.21 (0.30) 5.55 (0.21) 0.002
Fluorescein staining
 SICCA staining scorea 4.72 (0.25) 3.17 (0.22) < 0.001
 Oxford staining scorea 1.67 (0.10) 1.15 (0.09) < 0.001
Schirmer test (mm)a 10.65 (1.32) 11.12 (1.49) 0.703
Subjective symptom
 OSDI scorea 55.79 (3.18) 45.27 (2.98) 0.002
 Ocular irritation symptom scoreb 33 (73.3%) 24 (53.3%) < 0.001
  1. TBUT tear film break-up time, SICCA Sjögren’s International Collaborative Clinical Alliance, OSDI ocular surface disease index
  2. aResults are presented as mean (standard error) and P values are from linear mixed model
  3. bGeneralized estimating equations model for noncontinuous scale values: ocular irritation symptom score, n (%, proportion ≥ grade 2)