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Table 4 Correlation of CCT and CEC parameters with demographic and clinical variables

From: Profile of central corneal thickness and corneal endothelial cell morpho-density in healthy Congolese eyes

Variables

Pearson’s correlation coefficient (p-value)

Age

IOP

SE

CDR

BMI

OPP

Full set

 CCT

0.024 (0.69)

0.03 (0.62)

0.046 (0.44)

0.01 (0.85)

−0.12 (0.046)*

−0.084 (0.16)

 CECD

− 0.49 (< 0.001)*

− 0.13 (0.029)*

0.023 (0.71)

− 0.012 (0.85)

− 0.20 (0.001)*

−0.28 (< 0.001)*

 Cell size

0.45 (< 0.001)*

0.12 (0.04)*

−0.031 (0.61)

0.041 (0.50)

0.18 (0.004)*

0.29 (< 0.001)*

 CV

0.42 (< 0.001)*

0.13 (0.027)*

−0.034 (0.58)

0.007 (0.91)

0.19 (0.002)*

0.10 (0.08)

 HEX

−0.32 (< 0.001)*

− 0.091 (0.13)

− 0.047 (0.43)

0.056 (0.35)

− 0.17 (0.004)*

−0.16 (0.009)*

Subject < 50 years

 CCT

0.08 (0.25)

0.091 (0.20)

0.097 (0.18)

−0.03 (0.66)

−0.12 (0.09)

− 0.08 (0.28)

 CECD

−0.40 (< 0.001)*

− 0.05 (0.46)

0.01 (0.90)

0.06 (0.44)

− 0.17 (0.02)*

− 0.17 (0.018)*

 Cell size

0.36 (< 0.001)*

0.01 (0.90)

0.006 (0.94)

−0.03 (0.68)

0.14 (0.04)*

0.17 (0.02)*

 CV

0.32 (< 0.001)*

0.10 (0.16)

−0.04 (0.60)

−0.07 (0.32)

0.18 (0.01)*

0.05 (0.48)

 HEX

−0.33 (< 0.001)*

− 0.04 (0.60)

− 0.008 (0.92)

0.07 (0.32)

− 0.18 (0.014)*

−0.14 (0.044)*

  1. CCT Centra corneal thickness; CECD Corneal endothelial cell density; CV Coefficient of variation in cell size; HEX Hexagonality; IOP Intraocular pressure; SE Spherical equivalent; CDR Cup-to-disc ratio; BMI Body mass index; OPP Ocular perfusion pressure; *denotes significant correlation