Fig. 5

Quantification of the retinal neovascularization (NV) and avascular areas in P17 OIR mice. a: The retinal blood vessels were stained with isolectin B4 alone, FITC alone, and a combination of isolectin B4 and FITC-dextran. The remaining vitreous body vessels (arrow) and the unfilled small retinal vessels (arrow bead) were taken into consideration with regard to the estimation of the retinal NV or avascular areas. Original magnification, 50×; b and c: The retinal NV and avascular areas were evaluated by administration of isolectin B4 alone and FITC-dextran alone. n = 5 from 5 mice. *P < 0.05. The two groups were compared