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Table 3 Mixed effects models showing the correlation between OCTA parameters and the severity of DR

From: Quantitative analysis of retinal vessel density and thickness changes in diabetes mellitus evaluated using optical coherence tomography angiography: a cross-sectional study

Area Regression coefficient
DR severity # (Reference = controls)
No DR Mild NPDR Moderate NPDR Severe NPDR PDR
SVC_WholeETDRS −0.658* −0.223 − 0.797 − 4.608* − 2.689 − 2.491
SVC_ParaFovea − 0.861* − 0.283 − 1.013 − 4.928* − 3.851 −3.553
SVC_Para_T − 0.936* − 0.222 −0.738 − 5.208* − 2.806 − 4.310
SVC_Para_S − 0.664* − 0.182 − 0.263 − 4.169* −3.247 − 2.841
SVC_Para_N − 1.095 − 0.575 − 1.590 − 6.737* − 5.339 − 4.246
SVC_Para_I − 0.744* − 0.036 − 1.306 −3.662* − 3.263 − 2.976
SVC_PeriFovea − 0.611* − 0.191 − 0.691 − 4.593* −2.376 − 2.254
SVC_Peri_T −0.781* − 0.299 − 0.873 −3.799* − 2.160 −3.746
SVC_Peri_S − 0.706* − 0.418 − 1.365 − 5.276* −3.797 −2.226
SVC_Peri_N −0.395* − 0.038 − 0.377 −4.258* − 2.324 −0.894*
SVC_Peri_I −0.532* 0.008 −0.079 − 4.976* − 0.913 − 2.051
DVC_WholeETDRS −1.382* 0.101 −1.953 −7.022* −6.664 − 5.482*
DVC_ParaFovea −1.249* −0.001 − 1.655 − 6.091* − 6.828 −4.951*
DVC_Para_T − 1.209* −0.213 − 1.727 −5.968* − 6.406 −4.862*
DVC_Para_S − 1.203* 0.186 − 0.823 − 5.336* − 7.629 −4.998*
DVC_Para_N −1.137* 0.156 −1.415 −7.264* − 5.280 −4.151*
DVC_Para_I −1.470* −0.137 −2.658* −5.971* −7.875 − 5.977*
DVC_PeriFovea −1.468* 0.197 −2.073 −7.388* −6.775 −5.864*
DVC_Peri_T −1.320* −0.034 −1.745* −5.468* −5.890 − 5.849*
DVC_Peri_S −1.536* 0.117 −1.821 −7.664* −8.176 −6.126*
DVC_Peri_N −1.517* 0.383 −2.557 −8.744* −6.965 −5.450
DVC_Peri_I −1.530* 0.311 −2.249 −7.884* −5.889 −6.211
  1. Values are adjusted for age, duration, sex, mean arterial pressure, VA and OPP. # Defined as a continuous variable for the trend test. * P < 0.05 vs. control for the same region. Para parafoveal, Peri perifoveal, S superior, I inferior, T temporal, N nasal