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Table 4 Mixed effects models showing the correlation between retinal thickness and severity of DR

From: Quantitative analysis of retinal vessel density and thickness changes in diabetes mellitus evaluated using optical coherence tomography angiography: a cross-sectional study

Area

Regression coefficient

DR severity #

(Reference = controls)

No DR

Mild NPDR

Moderate NPDR

Severe NPDR

PDR

ILM-IPL Perifovea ALL

1.496*

0.233

0.756

8.423*

17.744*

3.525

ILM-IPL Perifovea T

1.475*

0.329

1.028

5.267

18.243*

4.153

ILM-IPL Perifovea S

1.497*

−2.026

−1.290

11.063*

11.696*

4.275

ILM-IPL Perifovea N

1.690*

1.111

2.058

10.980*

21.001*

3.264

ILM-IPL Perifovea I

1.439*

1.882

2.096

7.767*

22.804*

2.705

IPL-RPE Perifovea All

2.353*

0.857

2.998

7.692*

30.267*

5.826

IPL-RPE Perifovea T

3.434*

1.235

5.105*

14.098*

37.158*

9.216*

IPL-RPE Perifovea S

2.953*

1.040

3.462

6.848

42.838*

8.434*

IPL-RPE Perifovea N

1.422*

0.898

2.256

5.719

19.616*

2.985

IPL-RPE Perifovea I

1.486*

−0.031

1.299

4.169

20.428*

3.622

RPE-BRM Perifovea All

−0.215*

−0.515

−0.376

− 0.661

−1.065

−1.183*

RPE-BRM All

−0.219*

− 0.579

− 0.550

−0.491

−1.273

− 1.173*

ILM-RPE Perifovea All

3.820*

0.977

3.483

15.739*

47.388*

9.064

ILM-RPE Perifovea T

4.905*

1.537

6.075

19.287*

55.265*

13.313*

ILM-RPE Perifovea S

4.415*

−0.894

1.714

17.570*

54.373*

11.768*

ILM-RPE Perifovea N

3.074*

1.892

4.010

16.160*

39.819*

5.958

ILM-RPE Perifovea I

2.922*

1.676

3.200

11.550

42.469*

6.251

ILM-RPE Perifovea All

3.820*

0.977

3.483

15.739*

47.388*

9.064

  1. Values are adjusted for age, mean arterial pressure, sex, duration, VA and OPP. # Defined as a continuous variable for the trend test. * P < 0.05 vs. control for the same region. S superior, I inferior, T temporal, N nasal parts