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Table 4 Mixed effects models showing the correlation between retinal thickness and severity of DR

From: Quantitative analysis of retinal vessel density and thickness changes in diabetes mellitus evaluated using optical coherence tomography angiography: a cross-sectional study

Area Regression coefficient
DR severity # (Reference = controls)
No DR Mild NPDR Moderate NPDR Severe NPDR PDR
ILM-IPL Perifovea ALL 1.496* 0.233 0.756 8.423* 17.744* 3.525
ILM-IPL Perifovea T 1.475* 0.329 1.028 5.267 18.243* 4.153
ILM-IPL Perifovea S 1.497* −2.026 −1.290 11.063* 11.696* 4.275
ILM-IPL Perifovea N 1.690* 1.111 2.058 10.980* 21.001* 3.264
ILM-IPL Perifovea I 1.439* 1.882 2.096 7.767* 22.804* 2.705
IPL-RPE Perifovea All 2.353* 0.857 2.998 7.692* 30.267* 5.826
IPL-RPE Perifovea T 3.434* 1.235 5.105* 14.098* 37.158* 9.216*
IPL-RPE Perifovea S 2.953* 1.040 3.462 6.848 42.838* 8.434*
IPL-RPE Perifovea N 1.422* 0.898 2.256 5.719 19.616* 2.985
IPL-RPE Perifovea I 1.486* −0.031 1.299 4.169 20.428* 3.622
RPE-BRM Perifovea All −0.215* −0.515 −0.376 − 0.661 −1.065 −1.183*
RPE-BRM All −0.219* − 0.579 − 0.550 −0.491 −1.273 − 1.173*
ILM-RPE Perifovea All 3.820* 0.977 3.483 15.739* 47.388* 9.064
ILM-RPE Perifovea T 4.905* 1.537 6.075 19.287* 55.265* 13.313*
ILM-RPE Perifovea S 4.415* −0.894 1.714 17.570* 54.373* 11.768*
ILM-RPE Perifovea N 3.074* 1.892 4.010 16.160* 39.819* 5.958
ILM-RPE Perifovea I 2.922* 1.676 3.200 11.550 42.469* 6.251
ILM-RPE Perifovea All 3.820* 0.977 3.483 15.739* 47.388* 9.064
  1. Values are adjusted for age, mean arterial pressure, sex, duration, VA and OPP. # Defined as a continuous variable for the trend test. * P < 0.05 vs. control for the same region. S superior, I inferior, T temporal, N nasal parts