Skip to main content

Table 2 The confocal microscopy parameters of meibomian glands

From: In vivo confocal microscopy assessment of meibomian glands microstructure in patients with Graves’ orbitopathy

Parameters Active GO (34 eyes) Inactive GO (46 eyes) Control (62 eyes) P*
MOA, μm2 1985.82 ± 1325.30 2021.59 ± 1367.45 3896.63 ± 891.90 0.000a
MAD, /mm2 87.21 ± 32.69 80.72 ± 35.54 114.69 ± 34.90 0.000b
MALD, μm 118.11 ± 30.23 120.58 ± 27.64 58.68 ± 20.28 0.000c
MASD, μm 44.77 ± 19.16 46.02 ± 20.70 27.80 ± 9.90 0.000d
MAI 1.59 ± 0.60 1.26 ± 0.49 0.71 ± 0.61 0.000e
MSR 1.21 ± 0.40 1.76 ± 0.73 0.94 ± 0.67 0.000f
AWI 1.94 ± 0.76 0.89 ± 0.60 0.97 ± 0.74 0.000g
API 2.06 ± 0.68 1.04 ± 0.62 0.90 ± 0.64 0.000h
MF 0.65 ± 0.59 0.93 ± 0.48 0.37 ± 0.55 0.000i
  1. Data are presented as mean ± standard deviation (SD), n (%) or median (range), as appropriate
  2. MG Meibomian gland, MOA MG orifice area, MAD MG acinar density, MALD MG acinar longest diameter, MASD MG acinar shortest diameter, MAI MG acinar irregularity, MSR Meibum secretion reflectivity, AWI Acinar wall inhomogeneity, API Acinar periglandular interstices inhomogeneity, MF Severity of MG fibrosis
  3. *Obtained by Kruskal-Wallis test
  4. a Active GO vs. Inactive GO: P = 0.793; Active GO vs. Control: P = 0.000; Inactive GO vs. Control: P = 0.000 (Mann- Whitney U test)
  5. b Active GO vs. Inactive GO: P = 0.302; Active GO vs. Control: P = 0.001; Inactive GO vs. Control: P = 0.000 (Mann- Whitney U test)
  6. c Active GO vs. Inactive GO: P = 0.543; Active GO vs. Control: P = 0.000; Inactive GO vs. Control: P = 0.000 (Mann- Whitney U test)
  7. d Active GO vs. Inactive GO: P = 0.701; Active GO vs. Control: P = 0.000; Inactive GO vs. Control: P = 0.000 (Mann- Whitney U test)
  8. e Active GO vs. Inactive GO: P = 0.015; Active GO vs. Control: P = 0.000; Inactive GO vs. Control: P = 0.000 (Mann- Whitney U test)
  9. f Active GO vs. Inactive GO: P = 0.000; Active GO vs. Control: P = 0.040; Inactive GO vs. Control: P = 0.000 (Mann- Whitney U test)
  10. g Active GO vs. Inactive GO: P = 0.000; Active GO vs. Control: P = 0.000; Inactive GO vs. Control: P = 0.720 (Mann- Whitney U test)
  11. h Active GO vs. Inactive GO: P = 0.000; Active GO vs. Control: P = 0.000; Inactive GO vs. Control: P = 0.209 (Mann- Whitney U test)
  12. i Active GO vs. Inactive GO: P = 0.017; Active GO vs. Control: P = 0.020; Inactive GO vs. Control: P = 0.000 (Mann- Whitney U test)