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Table 2 Correlation between the N/T of mfERG, the macula thickness of OCT, and the mean thresholds and the total deviation of HFA 10–2 in each sector in glaucoma patients

From: Relationship between structural and functional changes in glaucomatous eyes: a multifocal electroretinogram study

OCT and HFA vs N/T (IQR: 0.59–1.024)
Parameter Sectors Coefficient 95% LCL 95% UCL P-value
GCIPL of OCT Average −3.455 −5.896 −1.014 0.009
Superotemporal −4.767 −7.592 −1.942 0.003
Superior −3.461 −6.021 − 0.901 0.014
Superonasal −5.311 −8.19 −2.433 0.001
Inferonasal −2.349 −7.199 2.501 0.578
Inferior −2.134 −6.211 1.943 0.522
Inferotemporal −3.027 −6.023 − 0.032 0.032
SN + IN/ST + IT −0.001 − 0.031 0.029 0.639
mRNFL of OCT Average −2.354 −4.136 −0.572 0.034
Superotemporal −3.665 −6.407 −0.923 0.026
Superior −4.455 −7.321 −1.589 0.008
Superonasal −2.546 −4.118 −0.973 0.007
Inferonasal 0.000 −2.590 2.591 0.775
Inferior −1.182 −4.261 1.897 0.624
Inferotemporal −2.706 −5.414 0.002 0.132
SN + IN/ST + IT 0.015 −0.016 0.045 0.632
GCC of OCT Average −5.809 −9.928 −1.691 0.017
Superotemporal −8.432 −13.613 −3.252 0.007
Superior −7.916 −13.221 −2.61 0.008
Superonasal −7.857 −12.041 −3.673 0.001
Inferonasal −2.349 −9.577 4.88 0.810
Inferior −3.316 −10.332 3.7 0.642
Inferotemporal −5.733 −10.939 −0.527 0.055
SN + IN/ST + IT 0.008 −0.016 0.033 0.735
Mean thresholds of HFA 10–2 Mean Deviation −2.089 −4.100 −0.077 0.069
Superotemporal −1.759 −4.173 0.656 0.231
Superior −4.302 −7.772 −0.833 0.045
Superonasal −4.437 −7.652 −1.223 0.020
Inferonasal 0.780 −1.728 3.287 0.425
Inferior −0.606 −2.360 1.149 0.773
Inferotemporal −0.864 −2.433 0.706 0.026
SN + IN/ST + IT 0.033 −0.104 0.169 0.083
Total deviation of HFA 10–2 Superotemporal −1.511 −3.588 0.567 0.097
Superior −4.329 −7.861 − 0.797 0.051
Superonasal −4.823 −8.172 −1.475 0.018
Inferonasal 0.356 −2.525 3.236 0.604
Inferior −0.282 −1.932 1.369 0.943
Inferotemporal −0.219 −1.012 0.573 0.569
SN + IN/ST + IT −0.890 −6.775 4.994 0.802
  1. Coefficient represents the increase in the value of parameter in each sector when N/T of mfERG changes by 75th percentile from 25th percentile. All multivariable regression models were adjusted for age and spherical equivalent
  2. N/T nasal to temporal amplitude ratio, mfERG multifocal electroretinogram, OCT Optical coherence tomopraphy, HFA 10–2 Humphrey Field Analyzer Program Central 10–2, IQR interquartile range (25th percentile – 75th percentile), LCL lower confidence limit, UCL upper confidence limit, GCIPL Ganglion cell-inner plexiform layer, SN Superonasal, IN Inferonasal, ST Superotemporal, IT Inferotemporal, mRNFL Macular retinal nerve fiber layer, GCC Ganglion cell complex
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BMC Ophthalmology

ISSN: 1471-2415

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