Fig. 3

Optic nerve head during treatment. OD and OS are on the left and right columns, respectively. (A) Three days after the first chemotherapy dose. Remarkable shrinkage of the white infiltrative mass was noticed. On OD, there were some whitish remnants on the vitreous inferiorly. (B) Ten days of treatment. Vitreous was clear OU and OD showed prominent peripapillary vascular tortuosity and a small pre-retinal hemorrhage, without signs of vascular occlusion. In the OS the superior and inferior disc margins were slightly blurry. (C) Twenty-one days of treatment. OD vascular tortuosity was less pronounced, and the hemorrhage had been absorbed. OS examination was unremarkable. (D) 60 days after allogenic transplantation. There was minor optic pallor OD temporally and vitreous was normal. OS remained unchanged