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Fig. 4 | BMC Ophthalmology

Fig. 4

From: Imaging mass cytometry for high-dimensional tissue profiling in the eye

Fig. 4

High-dimensional cellular profiling via clustering analysis. Each dot represents a single cell. A. t-SNE dimensionality reduction map, representing the different tissue conditions (blue: conjunctival melanoma; red: healthy conjunctiva). B. t-SNE map overlaid with the 24 differently colored Phenograph clusters, each color representing one cluster. C and D. t-SNE plots overlaid with the marker intensities of Ki-67 (C) and Pankeratin (D) showing Ki-67 and Pankeratin expression in cluster composed almost exclusively of melanoma cells or control conjunctival cells, respectively

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