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Fig. 3 | BMC Ophthalmology

Fig. 3

From: Variants identified by next-generation sequencing cause endoplasmic reticulum stress in Rhodopsin-associated retinitis pigmentosa

Fig. 3

Co-localization of rhodopsin with the ER marker. Immunofluorescent localization of GFP-fused Rhodopsin (green) and ER (red) in WT and mutant rhodopsin expressing cells. Nuclei were stained with Hoechst (blue). WT-rhodopsin expressing cells displayed plasma membrane (white arrow) and cytoplasmic staining patterns. In contrast, all three mutant Rhodopsin expressing cells (P23H, P53R and L95P) showed punctate co-localization patterns with the ER-Tracker Red (merge: yellow). Scale bar = 20 μm

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BMC Ophthalmology

ISSN: 1471-2415

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