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Table 3 Levels of cytokine (pg/mL, mean ± SD) in the aqueous humor in wet age-related macular degeneration patients

From: Aqueous humor cytokine levels through microarray analysis and a sub-analysis based on optical coherence tomography in wet age-related macular degeneration patients

 

SRF (n = 9)

PED (n = 8)

SRT (n = 8)

(+)

(−)

P*

(+)

(−)

P*

(+)

(−)

P*

IL-1α

18.5 ± 15.9

216.3 ± 199.5

0.036

15.1 ± 9.7

170 ± 192.6

0.622

90.8 ± 152.1

17.9 ± 8.7

0.833

GM-CSF

19.9 ± 11.4

71.0 ± 67.4

0.050

18.5 ± 10.9

72.9 ± 65.6

0.006

48.1 ± 50.6

14.7 ± 13.4

0.065

IFN-γ

264.6 ± 62.6

676.6 ± 611.8

0.076

262.5 ± 63.2

681.4 ± 607.3

0.034

487.0 ± 451.5

238.4 ± 43.2

0.045

MCP-1

984.1 ± 255.7

854.4 ± 266.1

0.503

964.3 ± 228.3

899.1 ± 343.3

0.284

963.8 ± 287.6

913.0 ± 710.1

0.622

MIP-1α

812.8 ± 545.3

330.9 ± 127.6

0.076

787.4 ± 561.3

388.1 ± 190.6

0.065

506.3 ± 276.0

917.7 ± 710.1

0.284

MIP-1β

38.2 ± 29.1

21.3 ± 13.0

0.414

34.0 ± 29.2

30.7 ± 20.2

0.724

27.5 ± 17.4

41.9 ± 36.5

0.622

TNFα

860.0 ± 225.2

1973.3 ± 1399.3

0.106

836.4 ± 216.7

2026.6 ± 1343.3

0.011

1409.4 ± 1100.2

871.6 ± 295.3

0.284

VEGF

189.2 ± 73.6

349.3 ± 327.7

0.076

165.0 ± 57.6

403.8 ± 289.9

0.354

283.7 ± 232.8

166.0 ± 60.5

0.524

  1. VEGF vascular endothelial growth factor
  2. *Mann-Whitney U test