Fig. 1

Effects of non-selective β-blocker levobunolol on corneal epithelial wound healing in mice. A The central region of corneal epithelium marked with 2.5 mm trephine was scraped and treated with saline (Ctrl) and non-selective β-blocker levobunolol (Levo), and then stained with fluorescein sodium every 12 h. B A graph of the epithelial defect area at 12 h was presented as the percentage of the original wound. C The central and limbal regions of the corneal epithelium with 3.0 mm trephine were scraped and treated with saline (Ctrl) and levobunolol (Levo), and then stained with fluorescein sodium at 12 h. D A graph of the epithelial defect area was presented as the percentage of the original wound. Data are representative of means ± SD. *P < 0.05, **P < 0.01