BMC Ophthalmology

Table 1 Single values of examined apoptosis and necrosis linked inflammatory cell mediators

From: Selective retina therapy and thermal stimulation of the retina: different regenerative properties - implications for AMD therapy

Gene	ApoE								NRF2
	TSR 1d		TSR 7d		SRT 1d		SRT 7d		TSR 1d		TSR 7d		SRT 1d		SRT 7d
	fold	p	fold	p	fold	p	fold	p	fold	p	fold	p	fold	p	fold	p
FasL	1.2		1.8		1.7		−2.5		−1.5		1.1		−1.3		1.3
IFNg	−5.1	< 0.01	1.6		−1.9		− 1.3		1.1		1.5		2.3	< 0.01	1.9
Il1b	−1.4		1.1		3.3		−1.7		−1.8		−1.8		−5.2		−2.0	0.02
Il18	1.4		1.1		1.6		−1.5		−1.6		1.1		−1.1		−1.3
NFkb1	−1.3		−1.6		5.0	< 0.01	1.3		−1.2		1.1		1.2		−1.7
C3	−1.9		1.1		4.0	0.01	− 1.4		−1.2		−1.8		1.2		−3.1
Tlr1	−1.2		1.6		2.1		− 1.7		−1.7		1.1		2.5	0.04	−1.4
Tlr2	−1.8		−1.1		4.1	< 0.01	−1.3		−1.9		1.2		−1.1		−1.1
Tlr4	−1.5		1.1		2.8	0.01	−1.1		−2.0	< 0.01	−1.1		1.5		−1.5
Tlr7	−1.3		1.6		1.9		−2.3		−2.3	0.05	1.7		1.2		−1.4
Tlr9	−1.7		1.1		4.0	< 0.01	−1.5		−3.0	< 0.01	−1.6		−1.6		−1.4
Tnfsf14	−3.5	< 0.01	2.6		1.1		−3.0		1.9		2.5		−2.5		1.3

Column 1 shows the name of the gene examined. For each genotype, x-fold expression in the treated eyes (TSR or SRT respectively) compared with untreated eyes and their p-values are given. FasL, Ifng, Il1b, Il18, Nfkb1 may be linked to apoptosis (bold frame). C3, Tlr1, 2, 4, 7, 9 and Tnfsf14 may be linked to necrosis

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