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Table 4 Brain regions with changed FCD values and its potential impact

From: Functional connectivity density alterations in children with strabismus and amblyopia based on resting-state functional magnetic resonance imaging (fMRI)

Brain region

Brain function

Anticipated results

Cerebellum

Regulating body balance and muscle tone; Coordinating of voluntary movement and language; emotion control; spatial cognition

The damage of spatial cognition

Lenticular nucleus, putamen

Executive ability; language function.

Impairment of font- semantic pathway in visual pathway

Superior frontal gyrus

Cognition; semantic system; episodic memory; indirectly control the sequences of visual-guided saccades and eye–hand coordination.

Reduced spatial cognitive ability; impairment of eye-hand coordination

Angular gyrus

Visual language center

Compensatory enhancement of visual image and auditory image connection

Middle cingulum gyrus

Executive ability; emotional management; visual function

Abnormality of visual function

Superior parietal gyrus

Center of tactile and stereognosis

Stereognosis consumption increased

Middle frontal gyrus

Consist of Frontal eye field

eye movements accuracy consumption increased

Temporal pole mid

Related to high-level social emotional function, implicated in theory of mind

Negative emotion, abnormal social function

Hippocampus

Long-term memory; associated with visual system; spatial information processing capability

The damage of spatial information processing capability

Thalamus

involved in visual sensation; dynamic visual information management

The capability of dynamic visual information processing is impacted