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Table 2 In silico analysis with predictive software

From: Novel SOX2 mutation in autosomal dominant cataract-microcornea syndrome

  SIFT MAPP MutationTaster2 PolyPhen-2 CADD REVEL
Predicted value D D D D 31 0.762
  1. D Damaging, Align GVGD Grantham Variation/Grantham Deviation, SIFT Sorting Tolerant From Intolerant, MAPP Map Annotator and Pathway Profiler, CADD Combined Annotation Dependent Depletion, REVEL Rare Exome Variant Ensemble Learner