Comparison of transepithelial and conventional photorefractive keratectomy in myopic and myopic astigmatism patients: a randomized contralateral trial

Table 3 Corneal epithelial defect (CED) area in arm A (n = 39 bilateral cases) and arm B (n = 33 bilateral cases)

	Method	Operation day	Day 1	Day 2	Day 3	3-day change	P-value^†
Arm A	tPRK	54.35 ± 5.26	36.97 ± 9.29	10.55 ± 6.90	1.17 ± 1.85	−55.60 ± 5.78	0.02
Arm A	mPRK	59.68 ± 7.34^*	38.02 ± 8.14	9.06 ± 6.29	0.61 ± 1.32	−61.68 ± 7.61	0.02
Arm B	tPRK	54.27 ± 4.76	37.34 ± 13.07	11.60 ± 9.10	2.28 ± 4.36	−53.77 ± 7.10	0.16
Arm B	aaPRK	64.96 ± 6.54^**	45.23 ± 7.36^*	14.80 ± 6.29	2.67 ± 3.82	−61.27 ± 7.12	0.16

tPRK Transepithelial photorefractive keratectomy, mPRK Mechanical PRK, aaPRK Alcohol assisted PRK
^†Based on three-day change of CED by random mixed-effect model adjusted for correlation of fellow eyes and follow-up times
All data are presented as Mean ± SD (mm²)
Bold values are statistically significant by random mixed-effect model adjusted for correlation of fellow eyes
*P<0.01
**P<0.001

ISSN: 1471-2415