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Table 1 Clinical characteristics of patients with different surgical procedures

From: Glaucoma and risk factors three years after congenital cataract surgery

 

Group 1

Group 2

Group 3

P-value 1

P-value 2

P-value 3

* P-value 1

* P-value 2

* P-value 3

Eyes, n

111

85

63

      

Right eye, n

57

43

34

      

Unilateral cataract, n (%)

61 (55.0)

22 (25.9)

7(11.1)

 < 0.001

 < 0.001

0.025

   

IOL implantation, n

 In-the-bag

109

68

–

      

 Sulcus

2

17

–

      

History of prematurity, n (%)

7 (6.3)

13 (15.3)

4 (6.4)

0.039

1.000

0.092

0.287

0.518

0.175

FHCC, n (%)

7 (6.3)

12 (14.1)

8 (12.7)

0.067

0.149

0.803

0.525

0.838

0.621

PFV, n (%)

16 (14.4)

17(20.0)

10(15.9)

0.300

0.795

0.520

0.015

0.037

0.566

Age at surgery (months), Median (IQR)

 Primary surgery

34.0 (15.0–46.0)

4.0 (3.0–5.0)

3.0 (2.0–4.0)

 < 0.001

 < 0.001

0.008

 < 0.001

 < 0.001

0.045

 Secondary surgery

–

34.0 (24.0–37.0)

–

      

Follow-up (months), Median (IQR)

39.0 (29.0–53.0)

50.0 (44.0–62.0)

35.0 (27.0–44.0)

 < 0.001

0.050

 < 0.001

 < 0.001

0.030

 < 0.001

IOP (mmHg), Mean ± SD

 Baseline 1

12.9 ± 3.1

12.4 ± 2.6

10.8 ± 2.7

0.176

 < 0.001

 < 0.001

0.292

 < 0.001

0.002

 Baseline 2

–

13.9 ± 2.7

–

      

 Latest follow-up

14.6 ± 3.1

16.8 ± 4.0

14.4 ± 3.1

 < 0.001

0.635

 < 0.001

0.001

0.503

 < 0.001

Pre-op HCD (mm), Mean ± SD

10.4 ± 0.6

9.4 ± 0.7

9.4 ± 1.0

 < 0.001

 < 0.001

0.982

 < 0.001

 < 0.001

0.903

Pre-op CCT (μm), Mean ± SD

541.1 ± 44.5

564.8 ± 49.7

574.6 ± 46.9

0.001

 < 0.001

0.230

0.012

0.002

0.359

Pre-op ACD (mm), Mean ± SD

2.9 ± 0.6

2.3 ± 0.4

2.4 ± 0.5

 < 0.001

 < 0.001

0.782

 < 0.001

 < 0.001

0.874

Pre-op LT (mm), Mean ± SD

3.7 ± 0.9

3.4 ± 1.0

3.1 ± 1.1

0.185

0.003

0.095

0.337

0.070

0.218

Pre-op AL (mm), Mean ± SD

21.5 ± 2.0

18.7 ± 1.1

17.9 ± 1.5

 < 0.001

 < 0.001

 < 0.001

 < 0.001

 < 0.001

0.006

Glaucoma, n (%)

0 (0)

6 (7.1)

4 (6.3)

0.006

0.016

1.000

0.025

0.144

0.894

Glaucoma suspect, n (%)

0 (0)

10 (11.8)

1 (1.6)

 < 0.001

0.362

0.025

0.010

0.304

0.058

Glaucoma-related adverse events, n (%)

0 (0)

16 (18.8)

5 (7.9)

 < 0.001

0.006

0.061

 < 0.001

0.070

0.127

Steroid-induced ocular hypertension, n (%)

5 (4.5)

17 (20.0)

5 (7.9)

0.001

0.499

0.041

0.009

0.211

0.038

  1. P-value 1: Group 1 vs Group 2; P-value 2: Group 1 vs Group 3; P-value 3: Group 2 vs Group 3
  2. * P values adjusted for unilateral cataract difference by generalised estimating equation
  3. Baseline 1, primary preoperative IOP; Baseline 2, secondary preoperative IOP
  4. IOL Intraocular lens, FHCC Family history of congenital cataract, PFV Persistent fetal vasculature, IQR Interquartile range, IOP Intraocular pressure, Pre-op Preoperative, HCD Horizontal corneal diameter, CCT Central corneal thickness, ACD Anterior chamber depth, LT Lens thickness, AL Axial length
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BMC Ophthalmology

ISSN: 1471-2415

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