Variable | Overall (n = 57) | CRVO (n = 15) | BRVO (n = 42) | P* | Naïve (n = 31) | Previously treated (n = 26) | P* |
---|---|---|---|---|---|---|---|
Type of RVO, n (%) | |||||||
CRVO | 15 (26.3) | N.A. | N.A. | N.A. | 9 (21.0) | 6 (23.1) | 0.7647 |
BRVO | 42 (73.7) | 22 (71.0) | 20 (76.9) | ||||
Treatment status, n (%) | |||||||
Naïve | 31 (54.4) | 9 (60.0) | 22 (52.4) | 0.7647a | N.A. | N.A. | N.A. |
Previously treated | 26 (45.6) | 6 (40.0) | 20 (47.6) | ||||
Age, years | |||||||
Mean (SD) | 72.4 (9.3) | 70.6 (9.1) | 73.0 (9.4) | 0.3994 | 72.3 (10.5) | 72.5 (7.9) | 0.8225 |
95% CI | 69.9 to 74.9 | 65.6 to 75.7 | 70.1 to 76.0 | 68.4 to 76.1 | 69.3 to 75.7 | ||
Sex, n (%) | |||||||
Women | 34 (59.6) | 10 (66.7) | 24 (57.1) | 0.5224 | 19 (61.3) | 15 (57.7) | 0.7846 |
Men | 23 (40.4) | 5 (33.3) | 18 (42.9) | 12 (38.7) | 11 (42.3) | ||
Eye, n (%) | |||||||
Right | 25 (43.9) | 5 (33.3 | 20 (47.6) | 0.3428 | 14 (45.2) | 11 (42.3) | 0.8303 |
Left | 32 (56.1) | 10 (66.7) | 22 (52.4) | 17 (54.8) | 15 (57.7) | ||
NOII | |||||||
Mean (SD) | 1.3 (1.7) | 1.1 (1.5) | 1.4 (1.8) | 0.5850 | 0.0 | 2.9 (1.4) | < 0.0001 |
95% CI | 0.8 to 1.8 | 0.2 to 1.9 | 0.8 to 1.9 | 0.0 to 0.0 | 2.3 to 3.4 | ||
Type of RVO-ME, n (%) | |||||||
SLRS | 2 (3.5) | 1 (6.7) | 1 (2.4) | 0.3056b | 2 (6.5) | 0 (0.0) | 0.1474b |
CME | 20 (35.1) | 3 (20.0) | 17 (40.5) | 6 (19.4) | 14 (53.8) | ||
SRD | 35 (61.4) | 11 (73.3) | 24 (57.1) | 23 (74.2) | 12 (46.2) | ||
Duration of RVO-ME, days | |||||||
Mean (SD) | 61.3 (81.6) | 60.7 (70.8) | 61.5 (85.9) | 0.8632 | 62.5 (94.3) | 59.9 (65.2) | 0.5424 |
95% CI | 39.7 to 83.0 | 21.5 to 99.9 | 34.8 to 84.3 | 27.9 to 97.1 | 33.6 to 86.2 | ||
BCVA** | |||||||
Mean (SD) | 55.2 (19.4) | 55.5 (15.7) | 55.1 (20.7) | 0.6738 | 55.0 (19.0) | 55.5 (20.3) | 0.7524 |
95% CI | 50.1 to 60.4 | 46.8 to 64.2 | 48.7 to 61.6 | 48.1 to 62.0 | 47.3 to 63.7 | ||
CRT, μm | |||||||
Mean (SD) | 567.6 (226.2) | 549.8 (158.7) | 573.9 (247.3) | 0.8420 | 617.7 (280.0) | 507.9 (117.1) | 0.2846 |
95% CI | 507.6 to627.6 | 461.9 to 637.7 | 496.9 to 651.0 | 515.0 to 720.4 | 460.6 to 555.1 | ||
NMCST500, μm | |||||||
Mean (SD) | 175.1 (53.6) | 180.2 (53.0) | 173.7 (54.3) | 0.6570 | 180.2 (54.6) | 169.1 (52.8) | 0.3610 |
95% CI | 160.9 to 189.4 | 150.9 to 209.5 | 156.4 to 190.3 | 160.2 to 200.2 | 147.8 to 190.4 | ||
NMCST1500, μm | |||||||
Mean (SD) | 180.6 (58.4) | 188.3 (60.6) | 177.9 (78.1) | 0.5742 | 183.5 (58.9) | 177.2 (58.7) | 0.5859 |
95% CI | 165.1 to 196.1 | 154.7 to 221.8 | 159.8 to 196.0 | 161.9 to 205.1 | 153.5 to 200.9 | ||
TMCST500, μm | |||||||
Mean (SD) | 189.6 (76.5) | 205.5 (118.5) | 183.9 (55.4) | 0.9278 | 186.4 (65.5) | 193.5 (89.1) | 0.6137 |
95% CI | 169.3 to 209.9 | 139.8 to 275.1 | 166.7 to 201.2 | 162.3 to 210.4 | 157.5 to 229.4 | ||
TMCST1500, μm | |||||||
Mean (SD) | 184.1 (56.5) | 194.1 (75.7) | 180.5 (48.4) | 0.5804 | 189.2 (61.4) | 178.0 (50.4) | 0.2866 |
95% CI | 169.1 to 199.1 | 152.1 to 236.0 | 165.5 to 195.6 | 166.7 to 211.8 | 157.6 to 198.4 | ||
CST, μm | |||||||
Mean (SD) | 184.1 (57.0) | 184.1 (67.3) | 184.1 (53.7) | 0.9494 | 186.8 (54.6) | 180.8 (60.6) | 0.5749 |
95% CI | 169.0 to 199.2 | 146.9 to 221.4 | 167.3 to 200.8 | 166.8 to 206.9 | 156.3 to 205.3 | ||
HRF, n (%) | |||||||
< 10 | 16 (28.1) | 3 (20.0) | 13 (31.0) | 0.3247b | 8 (25.8) | 8 (30.8) | 0.5098b |
10–20 | 23 (40.4) | 11 (73.3) | 12 (28.6) | 12 (38.7) | 11 (42.3) | ||
> 20 | 18 (31.6) | 1 (6.7) | 17 (40.5) | 11 (35.5) | 7 (26.9) | ||
DRIL, n (%) | |||||||
Yes | 34 (59.6) | 10 (66.7) | 24 (57.1) | 0.5582a | 20 (64.5) | 14 (53.8) | 0.4323a |
No | 23 (40.4) | 5 (33.3) | 18 (42.9) | 11 (35.5) | 12 (46.2) | ||
Cysts volume, μm3 | |||||||
Mean (SD) | 317.9 (145.4) | 285.7 (121.8) | 329.7 (152.8) | 0.3268 | 318.9 (154.6) | 316.9 (137.1) | 0.9084 |
95% CI | 279.0 to 356.9 | 218.2 to 353.1 | 281.5 to 378.0 | 261.2 to 376.6 | 261.5 to 372.2 | ||
Cysts, n (%) | |||||||
< 100 μm | 2 (3.6) | 1 (6.7) | 1 (2.4) | 0.2838b | 1 (3.3) | 1 (3.8) | 0.4658b |
100–200 μm | 12 (21.4) | 5 (33.3) | 7 (17.1) | 8 (26.7) | 4 (15.4) | ||
> 200 μm | 42 (75.0) | 9 (60.0) | 33 (80.5) | 21 (70.0) | 21 (80.8) | ||
ELM, n (%) | |||||||
Non-disrupted | 13 (22.8) | 2 (13.3) | 11 (26.2) | 0.2059b | 5 (16.1) | 8 (30.8) | 0.6727b |
Partially disrupted | 24 (42.1) | 6 (40.0) | 18 (42.9) | 16 (51.6) | 8 (30.8) | ||
Disrupted | 20 (35.1) | 7 (46.7) | 13 (31.0) | 10 (32.39 | 10 (38.5) | ||
SRF, n (%) | |||||||
Yes | 35 (61.4) | 11 (73.3) | 24 (57.1) | 0.3600a | 23 (74.2) | 12 (46.2) | 0.0548a |
No | 22 (38.6) | 4 (26.7) | 18 (42.9) | 8 (25.8) | 14 (53.8) | ||
SRF, μm | |||||||
Mean (SD) | 147.1 (112.2) | 103.8 (38.8) | 166.9 (129.0) | 0.1097 | 158.4 (129.6) | 125.3 (67.1) | 0.3943 |
95% CI | 108.5 to 185.6 | 77.8 to 129.9 | 112.4 to 221.4 | 102.3 to 214.4 | 82.7 to 168.0 |