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Table 2 Change in best corrected visual acuity (BCVA) according to different baseline characteristics

From: Optical coherence tomography biomarkers in patients with macular edema secondary to retinal vein occlusion treated with dexamethasone implant

 

Change in BCVA from baseline to month 6c, n (%)

≥ 5

≥ 10

≥ 15

≤5

pa

Diagnosis

 CRVO

5 (19.2)

5 (20.8)

5 (25.0)

9 (42.9)

0.0728b

 BRVO

21 (80.8)

19 (79.2)

15 (75.0)

12 (57.1)

Treatment status

 Naïve

18 (69.2)

18 (75.0)

14 (70.0)

9 (42.9)

0.0690b

 Previously treated

8 (30.8)

6 (25.0)

6 (30.0)

12 (57.1)

ME durationd

  ≤ 32 days

10 (38.5)

9 (37.5)

9 (45.0)

13 (61.9)

0.1010b

  > 32 days

16 (61.5)

15 (62.5)

11 (55.0)

8 (38.1)

Type of RVO-ME

 SLRS

0 (0.0)

0 (0.0)

0 (0.0)

2 (9.5)

0.1877

 CME

8 (30.8)

7 (29.4)

8 (40.0)

9 (42.9)

 SRD

18 (69.2)

17 (70.8)

12 (60.0)

10 (47.6)

HRF, n (%)

  < 10

5 (19.2)

4 (16.7)

5 (25.0)

6 (28.6)

0.7126

 10–20

14 (53.8)

13 (54.2)

7 (35.0)

7 (33.3)

  > 20

7 (26.9)

7 (29.2)

8 (40.0)

8 (38.1)

ELM, n (%)

 Non-disrupted

6 (23.1)

6 (25.0)

3 (15.0)

4 (19.0)

0.3960

 Partially disrupted

15 (57.7)

13 (54.2)

10 (50.0)

7 (33.3)

 Disrupted

5 (19.2)

5 (20.8)

7 (35.0)

10 (47.6)

DRIL, n (%)

 No

9 (34.6)

8 (33.3)

5 (25.0)

11 (52.4)

0.3391b

 Yes

17 (65.4)

16 (66.7)

15 (75.0)

10 (47.6)

Cysts, n (%)e

  < 100 μm

0 (0.0)

0 (0.0)

0 (0.0)

2 (10.0)

0.2014

 100–200 μm

7 (26.9)

6 (25.0)

3 (15.0)

3 (15.0)

  > 200 μm

19 (73.1)

18 (75.0)

17 (5.5)

15 (75.0)

  1. Abbreviations: BCVA Best corrected visual acuity, CRVO Central retinal vein occlusion, BRVO Branch retinal vein occlusion, EM Macular edema, RVO-ME Macular edema secondary to retinal vein occlusion, SLRS Sponge-like retinal swelling, CME Cystoid macular edema, SRD Serous retinal detachment, HRF Hyperreflective foci, ELM External limiting membrane, DRIL Disorganization of the retinal inner layers
  2. aChi-squared test
  3. bChi-squared for trend test
  4. cLetters in the Early Treatment Diabetic Retinopathy Study (ETDRS) charts
  5. dMedian split
  6. eFifty-six eyes