Fig. 2

Evolvement of MD, PSD of VF and BCVA in NMOSD-ON and IDON. A The evolvement of MD in NMOSD-ON and IDON. The MD in NMOSD-ON group was significantly less than IDON group (*). Both groups began to show significant improvement after 3 m (#). B The evolvement of PSD in NMOSD-ON and IDON. The PSD in NMOSD-ON group was significantly higher than IDON group (*). No significant evolvement was found within NMOSD-ON group. In IDON group, a significant difference to onset was found at ≥ 6 m (#). C The evolvement of BCVA in NMOSD-ON and IDON. The BCVA in the IDON group was significantly better than NMOSD-ON group at onset and ≥ 6 m (*). In NMOSD-ON group, significant improvement was found at 1 m and 3 m (#), while in IDON group, no significant improvement was found. NMOSD-ON: neuromyelitis optica spectrum disorder- optic neuritis, IDON: idiopathic optic neuritis, MD: mean defect, PSD: pattern standard deviation, BCVA: best corrected visual acuity (log MAR), P: P value, *: P < 0.05, the significant difference between two groups, #: P < 0.05, the significant difference between each follow-up, onset: at onset of optic neuritis, 1 m: at 1 month after onset, 3 m: at 3 months after onset, ≥ 6 m: at 6–12 months after onset