Fig. 4

Evolvement of MD, PSD of VF and BCVA in first-ever NMOSD-ON and IDON. A The evolvement of MD in first-ever NMOSD-ON and IDON. At 1 m and ≥ 6 m, the MD in the NMOSD-ON group was lower than the IDON group. But at onset and 3 m, the MD in the NMOSD-ON group was higher than the IDON group. B The evolvement of PSD in first-ever NMOSD-ON and IDON. The PSD in NMOSD-ON group was higher than IDON group at onset and each follow-up of ON attack. C The evolvement of BCVA in first-ever NMOSD-ON and IDON. In the NMOSD-ON group, BCVA was only significantly worse than the IDON group only at onset. NMOSD-ON: neuromyelitis optica spectrum disorder- optic neuritis, IDON: idiopathic optic neuritis, MD: mean defect, PSD: pattern standard deviation, BCVA: best corrected visual acuity (log MAR), P: P value, *P < 0.05, onset: at onset of optic neuritis, 1 m: at 1 month after onset, 3 m: at 3 months after onset, ≥ 6 m: at 6–12 months after onset