Fig. 1

Multimodal fundus images in active phase. A A color fundus photograph shows multifocal, small, yellow-white spots in the extrafovea. B A fundus autofluorescence image shows punctate hypo-autofluorescent lesions. C A fundus infrared image shows punctate hyper-reflective lesions and a relatively broad area of hypo-reflective lesions around them. D An optical coherence tomography (OCT) angiography image of a 3 × 3 mm² section of the outer retina to the choriocapillaris layer shows several deficits of the choriocapillaris compatible with focal ischemic areas and no relevant choroidal neovascularization. E, F Fluorescent fundus angiography images obtained at early (17 s) and late phases (15 min 13 s) show impregnation of the dye with staining phenomena and their increase in intensity without leakage phenomena, respectively. G, H Indocyanine green fundus angiography images obtained at early (17 s) and late phases (15 min 13 s) show macular hypo-cyanescent lesions and clarity of their margins, respectively. I, J Horizontal- and vertical-scan OCT images through the fovea show focal elevation of the retinal pigment epithelium (RPE) and breakthrough of the RPE with the accumulation of parafoveal subretinal hyperreflective material, referable to inflammatory elements, respectively. Infrared images, indicating scan line, showed multiple hyperreflective spots