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Table 3 The treatment of FEVR

From: Long-term clinical prognosis of 335 infant single-gene positive FEVR cases

Gene

Closed-V

LSV

PPV + Silicone oil/C3F8

SB

Cryotherapy

IVR

Laser coagulation

Strabotomy

Eyes

Percentage

Eyes

Percentage

Eyes

Percentage

Eyes

Percentage

Eyes

Percentage

Eyes

Percentage

Eyes

Percentage

Eyes

Percentage

LRP5 (n = 190)

22

11.6%

6

3.2%

9

4.7%

2

1.1%

1

0.5%

15

7.9%

17

8.9%

1

0.5%

FZD4 (n = 150)

20

13.3%

3

2.0%

6

4.0%

0

0.0%

0

0.0%

3

2.0%

11

7.3%

0

0.0%

KIF11 (n = 118)

19

16.1%

0

0.0%

3

2.5%

2

1.7%

0

0.0%

3

2.5%

2

1.7%

2

1.7%

NDP (n = 96)

30

31.3%

4

4.2%

2

2.1%

0

0.0%

0

0.0%

14

14.6%

5

5.2%

0

0.0%

TSPAN12 (n = 92)

6

6.5%

1

1.1%

1

1.1%

0

0.0%

1

1.1%

6

6.5%

4

4.3%

1

1.1%

ZNF408 (n = 24)

4

16.7%

0

0.0%

1

4.2%

0

0.0%

0

0.0%

0

0.0%

2

8.3%

0

0.0%

  1. Closed-V Closed vitrectomy, LSV Lens-sparing vitrectomy, PPV Pars plana vitrectomy, SB Scleral buckling, IVR Intravitreal injection of ranibizumab