Fig. 1

Calculation of capillary plexuses in normal control nonsmoking group with automated software (Optovue, Fremont, CA). Figure 1A represents the whole, foveal and parafoveal vessel density of deep capillary plexuses (DCP) in the normal control nonsmoking group measured by optical coherence tomography angiography (OCTA): the whole vessel density of DCP was 45.1%, the foveal vessel density of DCP was 35.3%, the parafoveal vessel density of DCP was 49.7%. Figure 1B represents the whole, foveal and parafoveal vessel density of superficial capillary plexuses (SCP) in the normal control nonsmoking group measured by optical coherence tomography angiography (OCTA): the whole vessel density of SCP was 50.9%, the foveal vessel density of SCP was 21.1%, the parafoveal vessel density of SCP was 53.5%