Table 5 Reduction of mean intraocular pressure at each time point after surgery in POAG

From: Risk factors for intraocular pressure elevation in a six-month period after ab interno trabeculotomy using a Kahook Dual Blade

	KDB alone
	IOP (mmHg)	Number of med. ± SD	Mean change from baseline ± SD	P value*
	Mean ± SD	Number of med. ± SD	(Ratio of mean change)	P value*
Baseline	25.30 ± 7.31	3.75 ± 1.02	Reference
Day 1	17.25 ± 7.03	0	8.05 ± 8.13 (-31.8)	< 0.001
Week 1	21.30 ± 7.48	1.25 ± 1.48	4.00 ± 8.19 (-15.8)	0.042
Month 1	25.80 ± 10.69	2.15 ± 2.03	0.50 ± 11.12 (1.98)	0.084
Month 3	19.25 ± 4.05	2.65 ± 1.69	6.05 ± 7.74 (-23.9)	0.002
Month 6	16.53 ± 3.12	3.16 ± 1.42	8.84 ± 6.90 (-34.9)	< 0.001
	KDB combined with phaco
	IOP (mmHg)	Number of med. ± SD	Mean change from baseline ± SD	P value*
	Mean ± SD	Number of med. ± SD	(Ratio of mean change)	P value*
Baseline	19.04 ± 4.97	3.67 ± 1.12	Reference
Day 1	16.42 ± 6.46	0	2.63 ± 7.75 (-13.8)	0.05
Week 1	17.93 ± 5.99	0.56 ± 1.05	1.21 ± 6.92 (-6.36)	0.302
Month 1	17.25 ± 3.38	1.11 ± 1.53	1.79 ± 5.22 (-9.40)	0.047
Month 3	16.22 ± 2.44	1.32 ± 1.45	2.82 ± 5.14 (-14.8)	0.002
Month 6	17.94 ± 3.92	1.63 ± 1.56	0.76 ± 5.44 (-23.9)	0.432

POAG primary open angle glaucoma, IOP intraocular pressure, KDB Kahook Dual Blade, phaco phacoemulsification, med. medications
^*P values were analysed by paired t test, and multiple comparisons were corrected using Bonferroni’s method, i.e., values of P < 0.05/4 were considered to be statistically significant

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