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Table 3 Subgroup analysis of the associations between NLR and diabetic retinopathy

From: The relationship between the neutrophil-to-lymphocyte ratio and diabetic retinopathy in adults from the United States: results from the National Health and nutrition examination survey

 

NLR

P for interaction

< 1.76

≥1.76, < 2.57

≥2.57

Gender

   

0.2452

 Male

1.0(ref)

1.259 (0.922, 1.719)

1.361 (1.005, 1.843)

 

 Female

1.0(ref)

1.046 (0.750, 1.458)

1.606 (1.166, 2.213)

 

Marital Status

   

0.1623

 Married

1.0(ref)

1.120 (0.828, 1.515)

1.721 (1.291, 2.294)

 

 Widowed/divorced

1.0(ref)

1.199 (0.820, 1.753)

1.183 (0.809, 1.729)

 

 Never married

1.0(ref)

1.833 (0.872, 3.854)

1.609 (0.747, 3.462)

 

Age, years

   

0.2286

  < 63

1.0(ref)

1.293 (0.946, 1.767)

1.823 (1.332, 2.495)

 

  ≥ 63

1.0(ref)

1.103 (0.798, 1.524)

1.278 (0.941, 1.737)

 

SBP, mmHg

   

0.4644

  < 130

1.0(ref)

1.138 (0.811, 1.596)

1.593 (1.145, 2.216)

 

  ≥ 130

1.0(ref)

1.229 (0.887, 1.702)

1.225 (0.891, 1.683)

 

DBP, mmHg

   

0.7890

  < 68

1.0(ref)

1.269 (0.888, 1.812)

1.411 (1.001, 1.988)

 

  ≥ 68

1.0(ref)

1.091 (0.797, 1.493)

1.332 (0.975, 1.819)

 

BMI, kg/m2

   

0.1015

  < 31.2

1.0(ref)

1.019 (0.735, 1.413)

1.520 (1.112, 2.078)

 

  ≥ 31.2

1.0(ref)

1.308 (0.952, 1.796)

1.364 (0.996, 1.867)

 

Waist circumference, cm

   

0.0241*

  < 107.6

1.0(ref)

1.010 (0.726, 1.406)

1.365 (0.982, 1.899)

 

  ≥ 107.6

1.0(ref)

1.386 (0.991, 1.938)

1.459 (1.054, 2.020)

 

Hemoglobin, g/dl

   

0.0085**

  < 13.6

1.0(ref)

1.217 (0.881, 1.679)

1.699 (1.252, 2.304)

 

  ≥ 13.6

1.0(ref)

1.198 (0.876, 1.639)

1.352 (0.988, 1.849)

 

PIR

   

0.2918

  < 1.7

1.0(ref)

1.326 (0.958, 1.835)

1.588 (1.152, 2.190)

 

  ≥ 1.7

1.0(ref)

1.120 (0.791, 1.586)

1.540 (1.105, 2.145)

 

TC, mg/dl

   

0.8835

  < 174

1.0(ref)

1.235 (0.897, 1.699)

1.325 (0.970, 1.809)

 

  ≥ 174

1.0(ref)

1.112 (0.802, 1.541)

1.629 (1.189, 2.232)

 

HDL, mg/dl

   

0.3069

  < 46

1.0(ref)

1.302 (0.946, 1.793)

1.478 (1.077, 2.027)

 

  ≥ 46

1.0(ref)

1.082 (0.781, 1.497)

1.492 (1.095, 2.031)

 

LDL, mg/dl

   

0.9532

  < 96

1.0(ref)

1.148 (0.700, 1.883)

1.285 (0.804, 2.053)

 

  ≥ 96

1.0(ref)

1.486 (0.908, 2.431) 1

1.595 (0.968, 2.631)

 

Triglycerides, mg/dl

   

0.6060

  < 120

1.0(ref)

1.391 (0.852, 2.274)

1.468 (0.919, 2.343)

 

  ≥ 120

1.0(ref)

1.187 (0.737, 1.911)

1.428 (0.889, 2.293)

 

HbA1c, %

   

0.4348

  < 7

1.0(ref)

1.265 (0.886, 1.806)

1.403 (0.988, 1.993)

 

  ≥ 7

1.0(ref)

1.147 (0.855, 1.540)

1.605 (1.207, 2.133)

 

CHD

   

0.4167

 Yes

1.0(ref)

1.325 (0.683, 2.571)

0.930 (0.486, 1.781)

 

 No

1.0(ref)

1.149 (0.903, 1.463)

1.621 (1.283, 2.047)

 

Stroke

   

0.6780

 Yes

1.0(ref)

1.569 (0.741, 3.320)

2.026 (0.991, 4.141)

 

 No

1.0(ref)

1.151 (0.908, 1.458)

1.446 (1.148, 1.823)

 

HF

   

0.4004

 Yes

1.0(ref)

1.349 (0.651, 2.796)

1.088 (0.552, 2.145)

 

 No

1.0(ref)

1.148 (0.904, 1.458)

1.513 (1.197, 1.913)

 
  1. NLR Neutrophil to lymphocyte ratio, SBP Systolic blood pressure, DBP Diastolic blood pressure, BMI Body mass index, PIR Poverty income ratio, TC Total cholesterol, HDL High density lipoprotein, LDL Low density lipoprotein, HbA1c Glycosylated hemoglobin A1c, CHD Coronary heart disease, HF Heart failure
  2. *P < 0.05, **P < 0.01
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