Ability of routinely collected clinical factors to predict good visual results after primary Descemet membrane endothelial keratoplasty: a cohort study

Table 2 Association between prognostic factors and BCVA of ≤0.1 LogMAR at 12 postoperative months

Factors	M12 BCVA ≤0.1 logMAR (n = 81)	M12 BCVA > 0.1 logMAR (n = 19)	Univariate^a p	Multivariate^b
Factors	M12 BCVA ≤0.1 logMAR (n = 81)	M12 BCVA > 0.1 logMAR (n = 19)	Univariate^a p	OR (95% CI)	p
Patient age, years	70 ± 9	77 ± 7	0.001	0.914 (0.846; 0.987)	0.02
Female sex	40 (59)	13 (68)	0.60	1.264 (0.386; 4.134)	0.70
Graft donor age, years	75 (70–82)	74 (56–85)	0.68	1.023 (0.980; 1.068)	0.31
Triple DMEK	38 (47)	5 (26)	0.13	2.875 (0.802; 10.304)	0.10
Preop BCVA, logMAR	0.5 (0.5–0.7)	0.7 (0.7–0.7)	0.25	0.922 (0.139; 6.130)	0.93
Preop ECD, cells/mm²	2535 ± 207	2549 ± 211	0.79	1.001 (0.998; 1.004)	0.46
Preop CCT, μm	620 (589–662)	620 (579–654)	0.64	1.003 (0.993; 1.013)	0.53
Mean ant. Keratometry, D	43.7 ± 1.5	43.4 ± 1.5	0.36	1.368 (0.887; 2.110)	0.16
One or more rebubbling	24 (29)	6 (32)	0.99	1.152 (0.341; 3.898)	0.82

The data are presented as mean ± standard deviation, median (interquartile range), or n (%), as appropriate
Akaike Information Criterion = 99.245
ant. Anterior, BCVA best spectacle-corrected visual acuity, CI confidence interval, CCT central corneal thickness, DMEK Descemet membrane endothelial keratoplasty, ECD endothelial cell density, M12 Month 12, OR Odds Ratio
^aStudent’s t-test, Wilcoxon, or Chi-squared test, as appropriate
^bLogistic regression

ISSN: 1471-2415