Fig. 1

Superficial retinal layer of SD-OCTA images in 3 × 3-mm areas around the fovea in healthy individuals. (A, B): original en face OMAG image. (C, D): vessel diameter map with binary vessels (inµm). (A-D): Representative eye from a healthy 23-year-old female subject. The yellow circles in (A) and (B) show visible macular arch ring shrink and break, and flow impairment region enlargement before and after drinking coffee. (C, D): red circles show that regions in dark red demonstrated a significant decrease in the superficial retinal layer from baseline to 2 h after drinking coffee