Fig. 7
From: Functions of retinal astrocytes and Müller cells in mammalian myopia
Schematic diagram of possible cellular and molecular mechanism in mice FDM. Astrocytes and Müller cells suffer from retina hypoxia, and work as an injury susceptor to regular the receptors or secreted proteins, thus work as a bridge to connect vessels and neurons. Finally, retinal signals transmitter to sclera and lead to the scleral remodeling and axial elongation in FDM. A possible mechanism for atropine treatment is that atropine targets on retinal neurons or glial cells and influence GABA release, which interplay with retinal glial cells, and finally protect FDM