Table 1 Review of literature: demographics and clinical presentation of published cases of acute annular outer retinopathy

Dang et al.

1

66

F

White

Both

Present

3 months

Present

N

OS: CF 1ft

OD: 20/500

Absent

Normal retinal architecture outside the zone of peripapillary atrophy

Oral prednisone 100 mg daily, taper over 1 month

Distinct and slightly irregular white border along the outer limit of the retinal atrophy

Y

Absent

Seetharam et al. (2015)

1

31

F

White

Right

Present

18 months

Present

N

20/40

Absent

Hyperreflectivity in the ONL and the HFL; marked atrophy of the outer retina within the white ring

None

Distinct white intraretinal line that crossed the macula that extended to the periphery

Y

Absent

Yokoyama et al. (2009)

1

33

F

N/A

Left

Present

15 months

Present

N

20/25

N/A

N/A

Oral prednisone 30 mg daily

OS: Numerous grayish white rings of different sizes peripheral to the vascular arcades;

OD: Peripapillary annular grayish white ring

N

N/A

Simunovic et al. (2009)

1

45

F

N/A

Right

Present

1 month

Present

N

20/25

N/A

N/A

N/A

Grey-white peripapillary deep retinal demarcation line

N/A

N/A

Tang et al. (2008)

2

43

F

Asian

Right

Present

2 years

N/A

N

20/50

Present

N/A

Oral prednisolone 60 mg daily, taper over 6 months

Whitish ring around optic disc; larger ring centered over the macula

N

Absent

35

M

Mixed

Left

Present

2 years

N/A

N

20/20

Present

N/A

Oral prednisone 40 mg daily. Then plasmapheresis + oral cyclophosphamide 150 mg daily, taper over 9 months

OS: Intraretinal whitish-gray ring that traversed 360° of the midperiphery;

OD: Whitish intraretinal patch along the temporal retina

Y

N/A

Mitamura et al. (2005) [4]

1

33

F

N/A

Left

Present

1 year

Absent

N

20/30

Present

N/A

None

Irregular, incomplete annular band of grey-white, deep retinal opacification surrounding the optic disc and extending through the foveal centre

Y

Present

Harino et al. (2004) [6]

1

65

M

N/A

Left

Present

2 years

Present

Pneumoconiosis 20 years prior to presentation

20/33

Present

N/A

Kallidinogenase tablets were initiated to improve circulation in the retina and choroid

Lesion surround optic disc well demarcated by a serpentine ring of orange pigment

N

Absent

Cheung et al. (2002) [5]

1

58

F

White

Left

Present

6 weeks

Absent

N

20/30

Present

N/A

Oral prednisolone 60 mg daily + Acyclovir 400 mg 4 times daily

Peripapillary, annular grey-white ring

N

Absent

Fekrat et al. (2000) [3]

4

79

M

White

Left

Present

5 years

Absent

N

20/40

Present

N/A

None

Irregular, imcomplete, annular, white outer retinal ring

Y

Absent

71

M

White

Right

Present

2 years

Present

N

20/100

Present

N/A

Oral prednisone 60 mg daily, taper over 4 months

Irregular white outer retinal rim

Y

Absent

29

F

White

Left

Present

6 years

Absent

N

20/25

Absent

N/A

Oral prednisone 60 mg daily, taper over 2 weeks

Irregular, incomplete annular band of white deep retinal opacification

N

Absent

32

F

White

Left

N/A

1 year

N/A

N

20/200

N/A

N/A

None

Annular lesion around the disk; white outer retinal line along the superonasal edge

Y

N/A

Gass et al. (1995) [1]

1

23

M

N/A

Left

Present

12 years

Absent

N

20/15

Present

N/A

None

Grey retinal ring in the supertemporal quadrant

N

Absent