Fig. 3
From: Von Hipple-Lindau disease complicated with central retinal vein occlusion: a case report
DNA analysis of the patients and family members. A The pedigree of the family with VHL c.208G > A. This family presents a co-segregation of genotypic phenotypes associated with VHL gene heterozygous mutation. B Sanger sequencing electropherogram showing compound heterozygous variant (black arrow) in VHL. C Conservation of E70 in VHL in different mammal, bird, and reptile species. The protein sequences of VHL orthologs at positions 59–100 are aligned. The red box indicates the position of E70