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Table 3 Correlations between questionnaires and ocular surface parameters in AIBD patients (n = 25)

From: Ocular surface disorders affect quality of life in patients with autoimmune blistering skin diseases: a cross-sectional study

 

OSDI

Schirmer I

TBUT

CFS

LIPCOF

MGS

DEL

SF-36 scales

 Composite score

-0.42*

0.48*

-0.10

-0.08

0.04

0.07

0.06

 PCS

-0.30

0.52**

-0.04

-0.26

-0.10

0.25

-0.04

 MCS

-0.42*

0.30

-0.15

0.09

0.20

-0.17

0.09

 PF

-0.41*

0.20

0.09

0.10

0.11

0.05

-0.13

 RP

-0.20

0.53**

-0.10

-0.08

-0.20

0.09

0.04

 BP

-0.17

0.21

0.07

-0.41

0.05

0.14

-0.12

 GH

-0.14

0.35

-0.12

-0.08

0.00

0.40*

0.05

 VT

-0.11

0.30

0.11

-0.19

0.04

0.08

-0.02

 SF

-0.32

0.24

-0.23

-0.13

-0.01

-0.04

0.16

 RE

-0.25

0.19

-0.13

0.25

0.28

-0.18

0.16

 MH

-0.67**

0.23

-0.12

-0.03

0.19

-0.11

-0.16

HADS

 Anxiety

0.33

-0.25

0.21

-0.05

-0.15

-0.04

0.16

 Depression

0.35

-0.01

0.37

-0.31

-0.29

-0.06

-0.07

PSQI

0.35

-0.32

0.25

0.04

0.12

-0.04

-0.08

HAQ-DI

0.27

-0.35

-0.17

0.39

0.04

-0.02

0.08

  1. Correlations between two continuous variables were computed using the Pearson correlation coefficient, or Spearman rank correlation for non-normally distributed data and rank data
  2. Higher scores in the SF-36 indicate better quality of life (note the negative correlation with OSDI, the positive correlation with Schirmer I test)
  3. AIBD Autoimmune blistering skin diseases, SF-36 Medical Outcomes Study 36-Item Short Form questionnaire, PCS Physical component summary, MCS Mental component summary, PF Physical functioning, RP Physical role functioning, BP Bodily pain, GH General health perceptions, VT Vitality, SF Social role functioning, RE Emotional role functioning, MH Mental health, HADS Hospital Anxiety and Depression Scale, PSQI Pittsburgh Sleep Quality Index, HAQ-DI Health Assessment Questionnaire-Disability Index, OSDI Ocular Surface Disease Index, TBUT Tear break-up time, CFS Corneal fluorescein staining, LIPCOF Lid-parallel conjunctival folds, MGS Meibomian gland secretion, DEL Dry eye level
  4. * Presents 0.01 < P < 0.05, ** presents 0.001 < P < 0.01, and the significant differences are bolded