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Table 2 Clinical characteristics of the Ologen-augmented (Phaco-Oloxen) and non-augmented (PhacoXen) groups in combined Xen gel stent implantation and phacoemulsification

From: Comparison of surgical outcomes with and without Ologen collagen matrix augmentation during XEN gel stent implantation

 

Phaco-Oloxen (n = 19)

PhacoXen (n = 12)

p-value

Age, years (mean ± SD)

65.53 ± 7.78

70.66 ± 7.20

0.164*

Gender, n, male:female (%)

10:9 (52.6%:47.4%)

6:6 (50.0%:50.0%)

0.886†

Laterality, n, OD:OS (%)

11:8 (57.9%:42.1%)

6:6 (50.0%:50.0%)

0.667†

HTN, n, yes:no (%)

6:13 (33.3%:66.7%)

6:6 (50.0%:50.0%)

0.452^

DM, n, yes:no (%)

3:16 (15.8%:84.2%)

3:9 (25.0%:75.0%)

0.653^

Preoperative visual acuity, logMAR (mean ± SD)

0.50 ± 0.47

0.30 ± 0.35

0.120*

Preoperative intraocular pressure, mmHg (mean ± SD)

18.05 ± 6.95

15.42 ± 5.65

0.306*

Prior glaucoma surgery, n yes:no (%)

1:17 (5.3%:94.7%)

0:12(0%:100%)

0.427^

Number of preoperative medications, n (mean ± SD)

3.57 ± 0.69

3.08 ± 0.79

0.101*

Preoperative diagnosis, n (%)

  

0.106†

Primary open-angle glaucoma

12 (63.2%)

4 (33.3%)

 

Secondary open-angle glaucoma

7 (36.8%)

8 (66.7%)

 

CCT, (mean ± SD)

528.84 ± 40.48

524.97 ± 42.50

0.683*

ECD, (mean ± SD)

2522.86 ± 384.39

2632.77 ± 353.25

0.367*

Axial length, mm, (mean ± SD)

23.75 ± 1.18

23.32 ± 1.69

0.646*

RNFL thickness, (mean ± SD)

65.21 ± 13.25

64.20 ± 10.51

0.872*

VFI, (mean ± SD)

40.47 ± 36.30

62.50 ± 34.46

0.243*

MD, (mean ± SD)

-20.37 ± 11.12

-13.30 ± 9.88

0.155*

PSD, (mean ± SD)

6.63 ± 3.84

6.29 ± 2.40

0.980*

  1. Abbreviations HTN Hypertension, DM Diabetic mellitus, CCT Central corneal thickness, ECD Endothelial cell density, RNFL Retinal nerve fiber layer, VFI Visual field index, MD Mean deviation, PSD Pattern standard deviation
  2. * Mann–Whitney U-test
  3. †Chi-square test ^ Fisher’s exact test