Fig. 4
Downregulated PCED1B-AS1 affected the levels of angiogenic and inflammatory molecules in human retinal Müller glial cells. A Human retinal Müller glial cells with PCED1B-AS1 siRNA-transfection or without were left untreated or treated with 25 mM glucose, levels of VEGF and MCP-1 in the culture media were quantified by ELISA. B Human retinal Müller glial cells with PCED1B-AS1 siRNA-transfection or without were left untreated or treated with 300 µM CoCl2, and levels of VEGF and MCP-1 in the culture media were quantified by ELISA. C Human retinal Müller glial cells with PCED1B-AS1 siRNA-transfection or without were left untreated or treated with 50 ng/ml TNF-α, and levels of VEGF and MCP-1 in the culture media were quantified by ELISA. *P < 0.05, **P < 0.001, ***P < 0.001 (Unpaired t-test)