Skip to main content
Fig. 2 | BMC Ophthalmology

Fig. 2

From: Blue light attenuates TGF-β2-induced epithelial-mesenchymal transition in human lens epithelial cells via autophagy impairment

Fig. 2

Blue light exposure inhibits TGF-β2-induced EMT in HLE-B3 cells. A HLE B3 cells were treated with 5 ng/ml TGF-β2 in the presence or absence of blue light exposure for 48 h. EMT markers were detected by Western blot analysis and densitometry was quantified. B qRT-PCR analysis of EMT markers after blue light exposure with or without TGF-β2. C Bright field optical microscope images of treated HLE-B3 cells. D Representative images of migrated cells in tower chambers following transwell migration assays after treatments. E Quantification of migrated cells. F Cell motility of treated HLE-B3 cells shown by wound-healing assay. G The data of wound-healing assay were quantified based on the percentage of the remaining wound length (the wound length at 0 h was considered 100%). All data were shown as mean ± SD. *P < 0.05, **P < 0.01, and ***P < 0.001

Back to article page