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Table 3 IOPc and IOPg reduction following LASIK and PRK procedures including paired (post-operative – pre-operative) IOP measurement changes

From: Goldmann and modified Goldmann tonometry measuring intraocular pressure changes in eyes which underwent myopic laser in situ Keratomileusis and photorefractive keratectomy

Procedural Changes in IOP

LASIK (n = 58)

T-test between groups p=

PRK (n = 62)

T-test between groups p =

IOPg (GAT)

    

Mean Pre-Op

14.8+/−3.0 (20,7)

 

14.3+/−2.6 (20,8)

 

Mean Post-Op

11.5+/−2.0 (18,8)

< 0.0001

12.4+/−3.1 (19,6)

< 0.0001

IOPc (Mod. GAT)

    

Mean Pre-Op

16.5+/−2.8 (22,10)

 

14.3+/−2.6 (20,8)

 

Mean Post Op

12.8+/−2.1 (18,10)

< 0.0001

13.3+/−3.0 (19,6)

< 0.0001

Paired Procedural IOP Change

    

IOPg (Post-Pre)

(−)3.27+/−3.2 (4,-10)

 

(−)1.92+/−3.6 (7,-10)

 

IOPc (Post-Pre)

(−)1.93+/−3.3 (8,-8)

< 0.0001

(−)1.06+/− 3.6 (7,-8)

< 0.0001

  1. IOPc and IOPg Reduction with Ablation Depth and CCT Reduction. Correlations to the measured parameters following LASIK and PRK were not statistically significant (Tables 4 and 5). It should be noted, however, that increased ablation depth and decreased CCT trended toward lower post-operative IOP measured with IOPc and IOPg (Fig. 2). The GAT reduction in IOP following LASIK was nearly significant following LASIK (−)0.24 mmHg/μm (p = 0.07)