Cornea and external eye diseases

Section edited by Penny Asbell

This section covers all aspects of corneal and external eye diseases, including surgical procedures, prevention, diagnosis and management. It also accepts basic science studies covering areas including, but not limited to, molecular and cellular biology, genetics and pathophysiology. Prospective clinical studies, especially randomized controlled trials are particularly welcome.

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  1. Case report

    Case report of ocular Kaposi’s sarcoma

    Kaposi’s sarcoma (KS) is generally considered a neoplastic disorder of vascular origin and occurs in patients with acquired immunodeficiency syndrome (AIDS) or who have received immunosuppressive treatments af...

    Jing Yang, Xiao-fang Yin, Yong-ping Li and Shi-you Zhou

    BMC Ophthalmology 2017 17:143

    Published on: 14 August 2017

  2. Research article

    A novel TRPM8 agonist relieves dry eye discomfort

    Physical cooling of the eye surface relieves ocular discomfort, but translating this event to drug treatment of dry eye discomfort not been studied. Here, we synthesized a water-soluble TRPM8 receptor agonist ...

    Jee Myung Yang, Fengxian Li, Qin Liu, Marco Rüedi, Edward Tak Wei, Michael Lentsman, Hyo Seok Lee, Won Choi, Seong Jin Kim and Kyung Chul Yoon

    BMC Ophthalmology 2017 17:101

    Published on: 26 June 2017

  3. Research article

    Comparison of the acute ocular manifestations of Stevens-Johnson syndrome and toxic epidermal necrolysis in Chinese eyes: a 15-year retrospective study

    Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but life-threatening conditions that initially affect the skin and mucous membranes. The aim of this study was to compare the acute ...

    Loraine L. W. Chow, Kendrick C. Shih, Johnny C. Y. Chan, Jimmy S. M. Lai and Alex L. K. Ng

    BMC Ophthalmology 2017 17:65

    Published on: 12 May 2017

  4. Case report

    In vivo confocal microscopy of pre-Descemet corneal dystrophy associated with X-linked ichthyosis: a case report

    Pre-Descemet corneal dystrophy (PDCD) is characterized by the presence of numerous, tiny, polymorphic opacities immediately anterior to Descemet membrane, which is a rare form of corneal stromal dystrophy and ...

    Hui Shi, Xiao-feng Qi, Tao-tao Liu, Qian Hao, Xiao-hong Li, Ling-ling Liang, Yi-miao Wang and Zhi-hua Cui

    BMC Ophthalmology 2017 17:29

    Published on: 16 March 2017

  5. Research article

    Analysis of novel Sjogren’s syndrome autoantibodies in patients with dry eyes

    Dry eye is a common problem in Ophthalmology and may occur for many reasons including Sjogren’s syndrome (SS). Recent studies have identified autoantibodies, anti-salivary gland protein 1 (SP1), anti-carbonic ...

    Sandra Everett, Sahana Vishwanath, Vanessa Cavero, Long Shen, Lakshmanan Suresh, Kishore Malyavantham, Norah Lincoff-Cohen and Julian L. Ambrus Jr.

    BMC Ophthalmology 2017 17:20

    Published on: 7 March 2017

  6. Case report

    Corneal vesicles accumulate collagen VI associated with tissue remodeling in apolipoprotein a-I deficiency: a case report

    Apo A-I deficiency clinically shows low serum levels of HDL cholesterol and corneal opacity at a young age. Histopathological evaluations of affected corneas are not enough, and the mechanism of corneal opacit...

    Hiroyuki Namba, Mari Narumi, Shinji Susa, Rintaro Ohe, Takeo Kato, Mitsunori Yamakawa and Hidetoshi Yamashita

    BMC Ophthalmology 2017 17:11

    Published on: 8 February 2017

  7. Research article

    Microbiological profile of corneal ulcer cases diagnosed in a tertiary care ophthalmological institute in Nepal

    Corneal ulcer, a major cause of monocular blindness in developing countries has consistently been listed as the major cause of blindness and visual disability in many of the developing nations in Asia, Africa ...

    Sharmila Suwal, Dinesh Bhandari, Pratigya Thapa, Mohan Krishna Shrestha and Jyoti Amatya

    BMC Ophthalmology 2016 16:209

    Published on: 29 November 2016

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