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Glaucoma

This section takes submissions looking at all aspects of the prevention, diagnosis and management of glaucoma. The section also welcomes basic science studies including molecular and cellular biology, genetics, pathophysiology and epidemiology. Prospective clinical studies, especially randomized controlled trials are encouraged.

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  1. Imaging mass cytometry (IMC) combines the principles of flow cytometry and mass spectrometry (MS) with laser scanning spatial resolution and offers unique advantages for the analysis of tissue samples in unpre...

    Authors: Anja Schlecht, Stefaniya Boneva, Henrike Salie, Saskia Killmer, Julian Wolf, Rozina Ida Hajdu, Claudia Auw-Haedrich, Hansjürgen Agostini, Thomas Reinhard, Günther Schlunck, Bertram Bengsch and Clemens AK Lange

    Citation: BMC Ophthalmology 2021 21:338

    Content type: Technical advance

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  2. The nasal to temporal amplitudes ratio (N/T) of multifocal electroretinography (mfERG) scans measured within 5° of the macula can be used to detect glaucomatous change. The photopic negative response (PhNR) of...

    Authors: Hiroki Tanaka, Kyoko Ishida, Kenji Ozawa, Takuma Ishihara, Akira Sawada, Kiyofumi Mochizuki and Tetsuya Yamamoto

    Citation: BMC Ophthalmology 2021 21:305

    Content type: Research article

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  3. EPO (erythropoietin) and PDGF (platelet derived growth factor) families are thought to be associated with angiogenesis under hypoxic condition. The sharp rise of intraocular pressure in acute primary angle clo...

    Authors: Jing Wang, Ming-shui Fu, Min-wen Zhou, Bi-lian Ke, Zhi-hua Zhang and Xun Xu

    Citation: BMC Ophthalmology 2021 21:297

    Content type: Research article

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  4. PreserFlo® MicroShunt (PM) (also known as InnFocus® MicroShunt) is a subconjunctival stent implanted ab externo via a minimally invasive surgical procedure. The current indication is progressive, mild to moderate...

    Authors: Roxane Bunod, Mathieu Robin, Juliette Buffault, Chafik Keilani, Antoine Labbé and Christophe Baudouin

    Citation: BMC Ophthalmology 2021 21:273

    Content type: Case report

    Published on:

  5. This report describes the design and methodology of the “Eyes of Africa: The Genetics of Blindness,” a collaborative study funded through the Human Heredity and Health in Africa (H3Africa) program of the Natio...

    Authors: Olusola Olawoye, Chimdi Chuka-Okosa, Onoja Akpa, Tony Realini, Michael Hauser and Adeyinka Ashaye

    Citation: BMC Ophthalmology 2021 21:272

    Content type: Study protocol

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  6. With the rapid development of intraocular collamer lens (ICL) operation, it is foreseeable that we will encounter a large number of glaucoma patients with ICL implantation history. However, our current underst...

    Authors: Wei Wei, Xueqing Yu, Lu Yang, Chan Xiong and Xu Zhang

    Citation: BMC Ophthalmology 2021 21:268

    Content type: Case report

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  7. Demographic, systemic and ocular factors may impact macular ganglion cell–inner plexiform layer (GCIPL) thickness measurements. This study aimed to investigate the influences of multiple potential determinants...

    Authors: Xiaoyu Xu, Hui Xiao, Kunbei Lai, Xinxing Guo, Jingyi Luo and Xing Liu

    Citation: BMC Ophthalmology 2021 21:267

    Content type: Research article

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  8. Glaucomatous eyes often show strong intraocular pressure (IOP) fluctuations and individual measurements at different time points are necessary for personalized therapy. To survey IOP variations 48-hours diurna...

    Authors: Marion Zimmermann, Bert C. Giers, Anna Beck, Katharina Bell, Herwig Zimmermann, Marlene Hechtner, Esther M. Hoffmann, Norbert Pfeiffer and Katrin Lorenz

    Citation: BMC Ophthalmology 2021 21:262

    Content type: Research article

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  9. Axenfeld-Rieger syndrome (ARS) is a rare autosomal dominant eye disorder that can also affect other organs of the human body. The condition is primarily characterized by the anterior segmental abnormalities of...

    Authors: Kinga Gołaszewska, Natalia Dub, Emil Saeed, Zofia Mariak and Joanna Konopińska

    Citation: BMC Ophthalmology 2021 21:154

    Content type: Case report

    Published on:

  10. Early recognition and management of baseline risk factors may play an important role in reducing glaucoma surgery burdens. However, no studies have investigated them using real-world data in Japan or other cou...

    Authors: Chikako Shirai, Satoru Tsuda, Kunio Tarasawa, Kiyohide Fushimi, Kenji Fujimori and Toru Nakazawa

    Citation: BMC Ophthalmology 2021 21:153

    Content type: Research article

    Published on:

  11. To assess the diagnostic capability of novel Bruch’s membrane opening (BMO)-based disc parameters, the BMO-minimum rim width (BMO-MRW) and the BMO-minimum rim area (BMO-MRA) in the Chinese population and compa...

    Authors: Ruoshi Li, Xia Wang, Yahui Wei, Yuan Fang, Tian Tian, Lei Kang, Mei Li, Yu Cai and Yingzi Pan

    Citation: BMC Ophthalmology 2021 21:151

    Content type: Research article

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  12. To report sampling of the trabecular meshwork using the TrabEx+ (MicroSurgical Technology, Redmond, Washington, USA) device in ab interno trabeculectomy. Specifically, this series focusses upon preservation of...

    Authors: Vipul Ramjiani, Hardeep-Singh Mudhar, Thomas Julian and Graham Auger

    Citation: BMC Ophthalmology 2021 21:138

    Content type: Research article

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  13. Anterior chamber angle anatomy in perspective of ocular biometry may be the key element to intraocular pressure (IOP) reduction, especially in glaucoma patients. We aim to investigate anterior chamber angle an...

    Authors: Giedre Pakuliene, Kirilas Zimarinas, Irena Nedzelskiene, Brent Siesky, Loreta Kuzmiene, Alon Harris and Ingrida Januleviciene

    Citation: BMC Ophthalmology 2021 21:127

    Content type: Research article

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  14. The purpose of this study is to report the safety and efficacy of pars plana glaucoma drainage devices with pars plana vitrectomy using one of the vitrectomy sclerotomy sites for tube placement in patients wit...

    Authors: Enchi Kristina Chang, Sanchay Gupta, Marika Chachanidze, John B. Miller, Ta Chen Chang and David A. Solá-Del Valle

    Citation: BMC Ophthalmology 2021 21:106

    Content type: Research article

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  15. The use of a tissue patch graft is common practice with a glaucoma drainage device (GDD). Patch grafts can be visible in the palpebral fissure and may be cosmetically displeasing for some patients. The aim of ...

    Authors: Doaa S. Milibari, Dalal Fatani, Abeer Ahmad, Ohoud Owaidhah, Saleh A. AlObeidan, Faisal A. Almobarak and Rizwan Malik

    Citation: BMC Ophthalmology 2021 21:99

    Content type: Research article

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  16. Glaucoma drainage implants have been used with increasing frequency for the management of glaucoma. Patients who are candidates for glaucoma drainage devices often have more severe disease and are at risk of v...

    Authors: Monica Kenney Ertel, Nathaniel Ryan Gelinas, Taylor John Slingsby, Leonard Keith Seibold, Malik Yaser Kahook and Jeffrey Raymond SooHoo

    Citation: BMC Ophthalmology 2021 21:74

    Content type: Case report

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  17. Solitary extramedullary plasmacytoma (SEP) is a localised proliferation of monoclonal plasma cells involving soft tissue with no or minimal bone marrow involvement and no other systemic evidence of multiple my...

    Authors: Tom Ayton, Svetlana Cherepanoff, David Gottlieb, William A. Sewell, Sandy Smith and Claire Hooper

    Citation: BMC Ophthalmology 2021 21:66

    Content type: Case report

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  18. To investigate long-term outcomes of prediction error after phacotrabeculectomy and to determine risk factors that may cause unstable prediction error after phacotrabeculectomy in glaucoma patients.

    Authors: Yeon Soo Kang, Mi Sun Sung, Hwan Heo, Yong Sok Ji and Sang Woo Park

    Citation: BMC Ophthalmology 2021 21:60

    Content type: Research article

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  19. Various surgical techniques have been described, to be combined with cataract surgery in glaucoma patients, aiming for an additional reduction of intraocular pressure (IOP), hence minimizing the burden of anti...

    Authors: Magda A. Torky, Yousef A. Alzafiri, Ameera G. Abdelhameed and Eman A. Awad

    Citation: BMC Ophthalmology 2021 21:53

    Content type: Research article

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  20. Adherence to chronic therapies is crucial to prevent the progression of disease, such as glaucoma. However, only a limited number of studies have investigated them using real-world data in Japan. This study ai...

    Authors: Chikako Shirai, Nobushige Matsuoka and Toru Nakazawa

    Citation: BMC Ophthalmology 2021 21:52

    Content type: Research article

    Published on:

  21. Precise optic disc size measurements based on anatomically exact disc margins are fundamental for a correct assessment of glaucoma suspects. Computerized imaging techniques, such as confocal-scanning-laser-tom...

    Authors: Ioana Maria Cazana, Daniel Böhringer, Thomas Reinhard, Charlotte Evers, Diana Engesser, Alexandra Anton and Jan Lübke

    Citation: BMC Ophthalmology 2021 21:31

    Content type: Research article

    Published on:

  22. Severe congenital ophthalmological malformations and glaucoma might be an important occasional feature in patients with Coffin-Siris syndrome (CSS), especially Coffin-Siris syndrome 9 (CSS9, OMIM #615866) caus...

    Authors: Heidi Diel, Can Ding, Franz Grehn, Panagiotis Chronopoulos, Oliver Bartsch and Esther M. Hoffmann

    Citation: BMC Ophthalmology 2021 21:28

    Content type: Case report

    Published on:

    The Correction to this article has been published in BMC Ophthalmology 2021 21:57

  23. To compare the aqueous humor (AH) and the serum clusterin levels of patients with pseudoexfoliation syndrome (PEX), pseudoexfoliation glaucoma (PEXG), and primary open-angle glaucoma (POAG) with each other and...

    Authors: Fuat Yavrum, Ufuk Elgin, Zeynep Adiyaman Kocer, Vildan Fidanci and Emine Sen

    Citation: BMC Ophthalmology 2021 21:25

    Content type: Research article

    Published on:

  24. Implantation of the posterior chamber phakic intraocular lens has been widely performed to correct high and extreme myopia. Chronic intraocular pressure (IOP) elevation may occur in its late postoperative peri...

    Authors: Rongrong Hu, Wei Xu, Baishuang Huang and Xiaoyu Wang

    Citation: BMC Ophthalmology 2021 21:20

    Content type: Case report

    Published on:

  25. Early detection of glaucoma is paramount to maintain patients’ eyesight, however glaucomatous vision loss tends to begin in the periphery with up to 50% of patients unaware they are affected. Because glaucomat...

    Authors: Anna Neustaeter, Ilja Nolte, Harold Snieder and Nomdo M. Jansonius

    Citation: BMC Ophthalmology 2021 21:18

    Content type: Study protocol

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  26. Sturge-Weber syndrome (SWS) is a sporadic congenital disorder, characterized by unilateral facial nevus flammeus associated with ipsilateral glaucoma, choroidal angioma and leptomeningeal hemangiomas. SWS can ...

    Authors: Hongxi Wang, Nana Dong, Li Tan and Chukai Huang

    Citation: BMC Ophthalmology 2021 21:6

    Content type: Case report

    Published on:

  27. The aim of this retrospective study was to compare the efficacy and safety profile of a single XEN-microstent in different types of primary and secondary open angle glaucoma.

    Authors: Marc Schargus, Theresa Theilig, Matus Rehak, Catharina Busch, Caroline Bormann and Jan Darius Unterlauft

    Citation: BMC Ophthalmology 2020 20:490

    Content type: Research article

    Published on:

  28. Anterior uveitis secondary to topical brimonidine administration is rare and not well-defined. In glaucoma patients using brimonidine, one must consider this phenomenon to avoid mis-diagnosis and over-treatmen...

    Authors: Susanne Hopf, Karl Mercieca, Norbert Pfeiffer and Verena Prokosch-Willing

    Citation: BMC Ophthalmology 2020 20:489

    Content type: Research article

    Published on:

  29. To evaluate the choroidal changes in Sturge-Weber syndrome (SWS) secondary glaucoma and non-glaucoma port-wine stain (PWS) patients by enhanced depth imaging optical coherence tomography (EDI-OCT).

    Authors: Yue Wu, Lulu Huang, Yixin Liu, Li Xu and Wenyi Guo

    Citation: BMC Ophthalmology 2020 20:477

    Content type: Research article

    Published on:

  30. Primary open-angle glaucoma (POAG) is a progressive neurodegenerative disease which leads to irreversible blindness. An elevated intraocular pressure (IOP) is considered to be the main risk factor for the dise...

    Authors: Hannah Weindler, Martin S. Spitzer, Maximilian Schultheiß and Robert Kromer

    Citation: BMC Ophthalmology 2020 20:444

    Content type: Research article

    Published on:

  31. To understand the differences between two different optical coherence tomography angiography (OCTA) devices in detecting glaucomatous from healthy eyes by comparing their vascular parameters, diagnostic accura...

    Authors: A. R. Kee, V. C. H. Yip, E. L. T. Tay, C. W. Lim, J. Cheng, H. Y. Teo, C. H. Chua and L. W. L. Yip

    Citation: BMC Ophthalmology 2020 20:440

    Content type: Research article

    Published on:

  32. Central retinal vein occlusion is a variable disease pattern. Preliminary stages of a complete occlusion of the central vein, wich are subsumed under the term venous stasis retinopathy, may occur as transient ...

    Authors: Julia V. Stingl, Laura Ponce Nunez, Alexander K. Schuster and Esther M. Hoffmann

    Citation: BMC Ophthalmology 2020 20:428

    Content type: Case report

    Published on:

  33. Driving simulators are a safe alternative to on-road vehicles for studying driving behavior in glaucoma drivers. Visual field (VF) loss severity is associated with higher driving simulator crash risk, though m...

    Authors: David E. Anderson, John P. Bader, Emily A. Boes, Meghal Gagrani, Lynette M. Smith, Jideofor K. Ndulue, Sachin Kedar, Vikas Gulati, Deepta A. Ghate and Matthew Rizzo

    Citation: BMC Ophthalmology 2020 20:419

    Content type: Research article

    Published on:

  34. Glaucoma surgery have been developed to lower intraocular pressure in a less invasive manner than traditional glaucoma surgery. The purpose of this article is to determine the outcome of using combined phacoem...

    Authors: Juan Carlos Izquierdo, Josefina Mejías, Laura Cañola-R, Natalia Agudelo and Bárbara Rubio

    Citation: BMC Ophthalmology 2020 20:406

    Content type: Research article

    Published on:

  35. The causal effects of plasma lipid concentrations and the risk of primary open angle glaucoma (POAG) are still unclear. Thus, the purpose of this study was to identify, applying a two-sample Mendelian randomiz...

    Authors: Mengqiao Xu, Shengguo Li, Jundong Zhu, Dawei Luo, Weitao Song and Minwen Zhou

    Citation: BMC Ophthalmology 2020 20:390

    Content type: Research article

    Published on:

  36. To compare the efficacy and safety of ab externo circumferential trabeculotomy (ECT) and canaloplasty on primary open angle glaucoma (POAG) patients with failed filtering surgery and intact schlemm’s canal (SC).

    Authors: Huaizhou Wang, Chen Xin, Ying Han, Yan Shi, Sarah Ziaei and Ningli Wang

    Citation: BMC Ophthalmology 2020 20:389

    Content type: Research article

    Published on:

  37. Nanophthalmos has a significant genetic background and disease-causing mutations have been recently been reported in the myelin regulatory factor (MYRF) gene. We report clinical features in a patient with nanopht...

    Authors: Joshua Hagedorn, Armin Avdic, Michael J. Schnieders, Benjamin R. Roos, Young H. Kwon, Arlene V. Drack, Erin A. Boese and John H. Fingert

    Citation: BMC Ophthalmology 2020 20:388

    Content type: Case report

    Published on:

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Annual Journal Metrics

  • Speed
    82 days to first decision for reviewed manuscripts only
    60 days to first decision for all manuscripts
    200 days from submission to acceptance
    16 days from acceptance to publication

    Citation Impact
    2.209 - 2-year Impact Factor
    2.446 - 5-year Impact Factor
    1.293 - SNIP (Source-Normalized Impact per Paper)
    0.877 - SJR (SCImago Journal Rank)

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