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Glaucoma

This section takes submissions looking at all aspects of the prevention, diagnosis and management of glaucoma. The section also welcomes basic science studies including molecular and cellular biology, genetics, pathophysiology and epidemiology. Prospective clinical studies, especially randomized controlled trials are encouraged.

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  1. Central retinal vein occlusion is a variable disease pattern. Preliminary stages of a complete occlusion of the central vein, wich are subsumed under the term venous stasis retinopathy, may occur as transient ...

    Authors: Julia V. Stingl, Laura Ponce Nunez, Alexander K. Schuster and Esther M. Hoffmann

    Citation: BMC Ophthalmology 2020 20:428

    Content type: Case report

    Published on:

  2. Driving simulators are a safe alternative to on-road vehicles for studying driving behavior in glaucoma drivers. Visual field (VF) loss severity is associated with higher driving simulator crash risk, though m...

    Authors: David E. Anderson, John P. Bader, Emily A. Boes, Meghal Gagrani, Lynette M. Smith, Jideofor K. Ndulue, Sachin Kedar, Vikas Gulati, Deepta A. Ghate and Matthew Rizzo

    Citation: BMC Ophthalmology 2020 20:419

    Content type: Research article

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  3. Glaucoma surgery have been developed to lower intraocular pressure in a less invasive manner than traditional glaucoma surgery. The purpose of this article is to determine the outcome of using combined phacoem...

    Authors: Juan Carlos Izquierdo, Josefina Mejías, Laura Cañola-R, Natalia Agudelo and Bárbara Rubio

    Citation: BMC Ophthalmology 2020 20:406

    Content type: Research article

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  4. The causal effects of plasma lipid concentrations and the risk of primary open angle glaucoma (POAG) are still unclear. Thus, the purpose of this study was to identify, applying a two-sample Mendelian randomiz...

    Authors: Mengqiao Xu, Shengguo Li, Jundong Zhu, Dawei Luo, Weitao Song and Minwen Zhou

    Citation: BMC Ophthalmology 2020 20:390

    Content type: Research article

    Published on:

  5. To compare the efficacy and safety of ab externo circumferential trabeculotomy (ECT) and canaloplasty on primary open angle glaucoma (POAG) patients with failed filtering surgery and intact schlemm’s canal (SC).

    Authors: Huaizhou Wang, Chen Xin, Ying Han, Yan Shi, Sarah Ziaei and Ningli Wang

    Citation: BMC Ophthalmology 2020 20:389

    Content type: Research article

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  6. Nanophthalmos has a significant genetic background and disease-causing mutations have been recently been reported in the myelin regulatory factor (MYRF) gene. We report clinical features in a patient with nanopht...

    Authors: Joshua Hagedorn, Armin Avdic, Michael J. Schnieders, Benjamin R. Roos, Young H. Kwon, Arlene V. Drack, Erin A. Boese and John H. Fingert

    Citation: BMC Ophthalmology 2020 20:388

    Content type: Case report

    Published on:

  7. The aim of the study is to evaluate the diagnostic ability of OCT parameters and retinal ganglion cells (RGCs) count in identify glaucomatous disease in myopic preperimetric eyes.

    Authors: Teresa Rolle, Beatrice Bonetti, Alberto Mazzucco and Laura Dallorto

    Citation: BMC Ophthalmology 2020 20:373

    Content type: Research article

    Published on:

  8. Eyemate® is a system for the continual monitoring of intraocular pressure (IOP), composed of an intraocular sensor, and a hand-held reader device. As the eyemate®-IO sensor communicates with the hand-held read...

    Authors: Azzurra Invernizzi, Shereif Haykal, Valeria Lo Faro, Vincenzo Pennisi and Lars Choritz

    Citation: BMC Ophthalmology 2020 20:357

    Content type: Research article

    Published on:

  9. To investigate the distribution of peripheral anterior chamber depth (ACD) and the relationship between peripheral ACD and gonioscopy compared to other ocular parameters for primary angle closure disease (PACD...

    Authors: Qin Luo, Wenwen Xue, Yin Yuan, Chaowei Fu, Jiangnan He, Haidong Zou, Xiaowei Tong, Richard K. Lee and Ling Ge

    Citation: BMC Ophthalmology 2020 20:353

    Content type: Research article

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  10. To determine if 3% diquafosol (DQS) can preserve the meibomian gland morphology in glaucoma patients treated with prostaglandin analogs (PGA) for a 12-month follow-up period.

    Authors: Yue Guo, Jun Young Ha, He Long Piao, Mi Sun Sung and Sang Woo Park

    Citation: BMC Ophthalmology 2020 20:277

    Content type: Research article

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  11. Ripasudil is approved in Japan for glaucoma or ocular hypertension (OH) when other treatments are ineffective or cannot be administered. Its long-term safety and efficacy are being examined in a post-marketing...

    Authors: Hidenobu Tanihara, Takahiko Kakuda, Tetsuro Sano, Takashi Kanno and Ryoji Gunji

    Citation: BMC Ophthalmology 2020 20:275

    Content type: Research article

    Published on:

    The Correction to this article has been published in BMC Ophthalmology 2020 20:362

  12. Autosomal recessive bestrophinopathy (ARB) is caused by homozygous or compound heterozygous mutations in the BEST1 gene and always accompanied with refractory angle-closure glaucoma (ACG). The exact mechanism for...

    Authors: Yan Shi, Jiaxin Tian, Ying Han, Julius Oatts and Ningli Wang

    Citation: BMC Ophthalmology 2020 20:271

    Content type: Case report

    Published on:

  13. To examine the speed and accuracy of saccadic eye movements during a novel eye tracking threshold visual field assessment and determine whether eye movement parameters may improve ability to detect glaucoma.

    Authors: Andrew J. Tatham, Ian C. Murray, Alice D. McTrusty, Lorraine A. Cameron, Antonios Perperidis, Harry M. Brash, Brian W. Fleck and Robert A. Minns

    Citation: BMC Ophthalmology 2020 20:259

    Content type: Research article

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  14. To determine the effect of various factors to the preservation rate of the conjunctival layer borderlines of glaucomatous eyes treated with anti-glaucoma eye drops.

    Authors: Makoto Gozawa, Yoshihiro Takamura, Kentaro Iwasaki, Shogo Arimura and Masaru Inatani

    Citation: BMC Ophthalmology 2020 20:244

    Content type: Research article

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  15. To compare the efficacy of phacoemulsification (PKE) combined with nonpenetrating deep sclerectomy (NPDS) with mitomycin C (MMC) versus XEN® gel stent with MMC.

    Authors: Vincent Theillac, Esther Blumen-Ohana, Jad Akesbi, Pascale Hamard, Alexandre Sellam, Emmanuelle Brasnu, Christophe Baudouin, Antoine Labbe and Jean-Philippe Nordmann

    Citation: BMC Ophthalmology 2020 20:231

    Content type: Research article

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  16. Poor persistence with glaucoma therapy can lead to disease progression and subsequent blindness. Persistence with second-line glaucoma combination treatment in a Japanese real-world setting and whether it diff...

    Authors: Kenji Kashiwagi, Eriko Chono, Sarah Koesters and Poh Sin Yap

    Citation: BMC Ophthalmology 2020 20:223

    Content type: Research article

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  17. To investigate the safety and efficacy of scleral concave pool trabeculectomy (SCPT) combined phacoemulsification for eyes with coexisting cataract and primary open-angle glaucoma (POAG).

    Authors: Xiangxiang Ye, Yongjun Qi, Jianhua Deng, Yang Yang, Ting Mo, Mao Xu and Wanjun Liu

    Citation: BMC Ophthalmology 2020 20:222

    Content type: Research article

    Published on:

  18. To introduce a novel protocol to treat refractory acute primary angle closure (APAC): transscleral cyclophotocoagulation (TCP) followed by cataract surgery.

    Authors: Wei Liu, Luning Qin, Chenjia Xu, Dandan Huang, Ruru Guo, Jian Ji and Nomdo M. Jansonius

    Citation: BMC Ophthalmology 2020 20:209

    Content type: Research article

    Published on:

  19. To investigate the diagnostic power of radial peripapillary capillary (RPC) density, measured with optical coherence tomography angiography (OCT-A), in patients with superior segmental optic hypoplasia (SSOH).

    Authors: Maiko Abe, Kazuko Omodaka, Tsutomu Kikawa and Toru Nakazawa

    Citation: BMC Ophthalmology 2020 20:199

    Content type: Research article

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  20. The surgical management of glaucoma associated with Axenfeld-Rieger Syndrome (ARS) is poorly described in the literature. The goal of this study is to compare the effectiveness of various glaucoma surgeries on...

    Authors: Emily M. Zepeda, Kari Branham, Sayoko E. Moroi and Brenda L. Bohnsack

    Citation: BMC Ophthalmology 2020 20:172

    Content type: Research article

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  21. To investigate the long term surgical outcomes of cataract surgery in severe and end stage glaucoma patients with preoperative intraocular pressure less than 21 mmHg, and to detect the associated factors.

    Authors: Lin Fu, Yau Kei Chan, Junhua Li, Li Nie, Na Li and Weihua Pan

    Citation: BMC Ophthalmology 2020 20:160

    Content type: Research article

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  22. In order to detect glaucomatous optic nerve damages early on and evaluate the severity of glaucoma, a previously developed analytic method based on photographic retinal nerve fiber layer (RNFL) angle defect wa...

    Authors: Alexander Chen, Ing-Chou Lai, Wan-Hua Cho, Hung-Yin Lai, Pei-Wen Lin, Pei-Chang Wu and Ming-Tse Kuo

    Citation: BMC Ophthalmology 2020 20:141

    Content type: Research article

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  23. To compare the anterior biometrics in eyes with secondary acute angle closure induced by occult lens subluxation (ASAC-LS), misdiagnosed as acute primary angle closure (APAC) at the first visit with APAC, chro...

    Authors: Xiaoli Xing, Liangyu Huang, Fang Tian, Yan Zhang, Yingjuan Lv, Wei Liu and Aihua Liu

    Citation: BMC Ophthalmology 2020 20:87

    Content type: Research article

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  24. Tear film stability is the key event in ocular surface diseases. The purpose of this study is to evaluate spatial and temporal progression of the tear film breakup using an automatic non-invasive device.

    Authors: Adriano Guarnieri, Elena Carnero, Anne-Marie Bleau, Nicolás López de Aguileta Castaño, Marcos Llorente Ortega and Javier Moreno-Montañés

    Citation: BMC Ophthalmology 2020 20:12

    Content type: Research article

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  25. Glaucoma is a global public health problem and it is the leading cause of irreversible blindness worldwide. Even though public knowledge of glaucoma is a key for early case identification and prevention of bli...

    Authors: Zewdu Yenegeta, Ayanaw Tsega, Yezinash Addis and Fisseha Admassu

    Citation: BMC Ophthalmology 2020 20:8

    Content type: Research article

    Published on:

  26. XEN® gel stent (Allergan, Dublin/Republic of Ireland) is a relatively new microinvasive glaucoma device providing an ab-interno approach to the subconjunctival space for aqueous drainage and reduction of intra...

    Authors: Chandni Gupta and Divya Mathews

    Citation: BMC Ophthalmology 2019 19:253

    Content type: Case report

    Published on:

  27. The subconjunctival anesthesia with local anesthetics is considered as a low-risk procedure allowing ocular surgery without serious complications typical for retro- or parabulbar anesthesia, especially in pati...

    Authors: Katharina Knoll, Kristine Chobanyan-Jürgens, Dirk O. Stichtenoth, Ingo Roland Volkmann, Katerina Hufendiek and Carsten Framme

    Citation: BMC Ophthalmology 2019 19:195

    Content type: Case report

    Published on:

  28. A patient’s perception of how their glaucoma is managed will influence both adherence to their medication and outcome measures such as quality of life.

    Authors: Alison Fraenkel, Graham A. Lee, Stephen J Vincent, Roslyn A. Vincent, Rupert R. A. Bourne and Peter Shah

    Citation: BMC Ophthalmology 2019 19:192

    Content type: Research article

    Published on:

  29. The object of this study is to investigate the effect of early bleb parameters measured by three-dimensional anterior-segment optical coherence tomography on the surgical success of trabeculectomy.

    Authors: Utako Tsutsumi-Kuroda, Sachi Kojima, Ayako Fukushima, Kei-Ichi Nakashima, Keiichiro Iwao, Hidenobu Tanihara and Toshihiro Inoue

    Citation: BMC Ophthalmology 2019 19:155

    Content type: Research article

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  30. Interface fluid syndrome (IFS) is an unusual complication after laser-assisted in-situ keratomileusis (LASIK). We report the first case of IFS after uncomplicated phacotrabeculectomy in a patient who had under...

    Authors: Chung Young Kim, Young Ho Jung, Eun Ji Lee, Joon Young Hyon, Kyu Hyung Park and Tae Woo Kim

    Citation: BMC Ophthalmology 2019 19:74

    Content type: Case report

    Published on:

  31. Diabetic macular edema (DME) can be treated with different alternatives, among them Dexamethasone intravitreal implant 0.7 mg (DEX 0.7) has demonstrated that may improve both central macular thickness (CMT) an...

    Authors: Verónica Castro-Navarro, Enrique Cervera-Taulet, Catalina Navarro-Palop, Clara Monferrer-Adsuara, Laura Hernández-Bel and Javier Montero-Hernández

    Citation: BMC Ophthalmology 2019 19:15

    Content type: Research article

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  32. Central corneal thickness (CCT) has long been implicated to affect glaucoma predisposition. Several reports have identified that thinner CCT is a risk factor for open-angle glaucoma, and that CCT can be very v...

    Authors: Sana’ Muhsen, Feras Alkhalaileh, Mohammad Hamdan and Saif Aldeen AlRyalat

    Citation: BMC Ophthalmology 2018 18:279

    Content type: Research article

    Published on:

  33. To describe a unique case of decompression retinopathy manifesting as pre-macular subhyaloid hemorrhage that occurs in a nine-day old child after undergoing a non-penetrating deep sclerectomy for primary conge...

    Authors: Prithvi Ramtohul, Maëva Chardavoine, Marie Beylerian, Aurore Aziz, Frédéric Matonti and Danièle Denis

    Citation: BMC Ophthalmology 2018 18:240

    Content type: Case report

    Published on:

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