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Section edited by Luca Rossetti

This section takes submissions looking at all aspects of the prevention, diagnosis and management of glaucoma. The section also welcomes basic science studies including molecular and cellular biology, genetics, pathophysiology and epidemiology. Prospective clinical studies, especially randomized controlled trials are encouraged.

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  1. Content type: Research article

    The object of this study is to investigate the effect of early bleb parameters measured by three-dimensional anterior-segment optical coherence tomography on the surgical success of trabeculectomy.

    Authors: Utako Tsutsumi-Kuroda, Sachi Kojima, Ayako Fukushima, Kei-Ichi Nakashima, Keiichiro Iwao, Hidenobu Tanihara and Toshihiro Inoue

    Citation: BMC Ophthalmology 2019 19:155

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  2. Content type: Research article

    The effect of cataract surgery on IOP in patients with primary open-angle glaucoma (POAG) is a subject of debate. We investigated the effect of cataract surgery by phacoemulsification on intraocular pressure (...

    Authors: Loic Majstruk, Benjamin Leray, Aymeric Bouillot, Sylvain Michée, Gilles Sultan, Christophe Baudouin and Antoine Labbé

    Citation: BMC Ophthalmology 2019 19:149

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  3. Content type: Research article

    This comparative study aimed to demonstrate the differences between swept source OCT (SS-OCT) (1310 nm) and spectral domain OCT (SD-OCT) (840 nm) for the identification and measurement of anterior chamber angl...

    Authors: Yunsheng Qiao, Chen Tan, Min Zhang, Xinghuai Sun and Junyi Chen

    Citation: BMC Ophthalmology 2019 19:142

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  4. Content type: Research article

    Although the pathogenesis of glaucoma is not fully understood,an elevated intraocular pressure (IOP) is a major factor contributing to its development and progression. The aim of this study was to investigate ...

    Authors: Zi-wei Ma, Wen-han Qiu, Dan-ni Zhou, Wei-hua Yang, Xue-feng Pan and Hong Chen

    Citation: BMC Ophthalmology 2019 19:132

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  5. Content type: Research article

    The objective of this study is to evaluate and compare the short-term efficacy and safety of Ex-PRESS® mini shunt surgery and trabeculectomy for neovascular glaucoma (NVG).

    Authors: Kazuyuki Kawabata, Kohei Shobayashi, Keiichiro Iwao, Eri Takahashi, Hidenobu Tanihara and Toshihiro Inoue

    Citation: BMC Ophthalmology 2019 19:75

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  6. Content type: Case report

    Interface fluid syndrome (IFS) is an unusual complication after laser-assisted in-situ keratomileusis (LASIK). We report the first case of IFS after uncomplicated phacotrabeculectomy in a patient who had under...

    Authors: Chung Young Kim, Young Ho Jung, Eun Ji Lee, Joon Young Hyon, Kyu Hyung Park and Tae Woo Kim

    Citation: BMC Ophthalmology 2019 19:74

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  7. Content type: Research article

    Patients with primary angle closure/glaucoma (PAC/PACG) with extensive peripheral anterior synechiae (PAS), and coexisting cataract, increasingly have been treated with phacoemulsification combined with gonios...

    Authors: Tian Tian, Mei Li, Yingzi Pan, Yu Cai and Yuan Fang

    Citation: BMC Ophthalmology 2019 19:65

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  8. Content type: Research article

    To investigate structural and functional correlations in glaucoma patients using enhanced depth imaging spectral-domain optical coherence tomography (EDI OCT)-derived parameters.

    Authors: Flavio S. Lopes, Igor Matsubara, Izabela Almeida, Syril K. Dorairaj, Roberto M. Vessani, Augusto Paranhos Jr and Tiago S. Prata

    Citation: BMC Ophthalmology 2019 19:52

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  9. Content type: Research article

    Migraine is linked to endothelial dysfunction and is considered to be a systemic vasculopathy. Interestingly, systemic vascular diseases also occur in glaucoma patients and are considered to be vascular risk f...

    Authors: Jehn-Yu Huang, Chien-Chia Su, Tsing-Hong Wang and I-Ju Tsai

    Citation: BMC Ophthalmology 2019 19:50

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  10. Content type: Research article

    To investigate the occurrence of ciliochoroidal detachment (CCD), its risk factors and its impact on the success rate after Ahmed glaucoma valve (AGV) implantation.

    Authors: Lin Fu, Yau Kei Chan, Li Nie, Qi Dai, Zhenbin Qian, Kendrick Co Shih, Jimmy Shiu Ming Lai, Rong Huang and Weihua Pan

    Citation: BMC Ophthalmology 2019 19:46

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  11. Content type: Research article

    To study the efficacy of the biodegradable collagen implant Ologen® as an adjuvant in phaco-viscocanalostomy in patients with coexisting cataract and primary open angle glaucoma.

    Authors: Ahmed A. M. Gad, Bahaa-Eldin Hasan Abdulhalim, Ayman Lotfy, Ayman Mohamed Abdelrahman and Ahmed Samir Ahmed

    Citation: BMC Ophthalmology 2019 19:45

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  12. Content type: Research article

    To investigate the expression of Matrix Metalloproteinases 2 and aquaporin-1 in corneoscleral junction and explore the mechanism of trabecular damageafter angle-closure.

    Authors: Yaqin Jiang, Canwei Zhang, Jianli Ma, Luping Wang, Jing Gao, Jiantao Ren, Wei He, Sheng Wang, Shuai Sheng and Xudong Huang

    Citation: BMC Ophthalmology 2019 19:43

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  13. Content type: Research article

    To measure peripapillary retinal nerve fiber layer (RNFL) thickness and posterior pole retinal thickness in primary angle-closure suspects (PACS) by Spectral domain optical coherence tomography (SD-OCT) and to...

    Authors: Yi Zha, Wei Huang, Jinfei Zhuang and Jianqiu Cai

    Citation: BMC Ophthalmology 2019 19:36

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  14. Content type: Research article

    The purpose of this study was to evaluate the changes in choroidal thickness and lamina cribrosa position after nonpenetrating deep sclerectomy (NPDS) and trabeculectomy.

    Authors: Aymeric Bouillot, Alexandra Pierru, Esther Blumen-Ohana, Emmanuelle Brasnu, Christophe Baudouin and Antoine Labbé

    Citation: BMC Ophthalmology 2019 19:24

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  15. Content type: Research article

    Diabetic macular edema (DME) can be treated with different alternatives, among them Dexamethasone intravitreal implant 0.7 mg (DEX 0.7) has demonstrated that may improve both central macular thickness (CMT) an...

    Authors: Verónica Castro-Navarro, Enrique Cervera-Taulet, Catalina Navarro-Palop, Clara Monferrer-Adsuara, Laura Hernández-Bel and Javier Montero-Hernández

    Citation: BMC Ophthalmology 2019 19:15

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  16. Content type: Research article

    To assess a possible signal drift, noise and influences of electromagnetic radiation on the measurement behaviour of the Triggerfish® contact lens sensor, which might be mistaken as IOP fluctuations.

    Authors: Dieter Franz Rabensteiner, Jasmin Rabensteiner and Christoph Faschinger

    Citation: BMC Ophthalmology 2018 18:338

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  17. Content type: Case report

    Leber’s hereditary optic neuropathy (LHON) is a maternally inherited recessive disease rarely complicated with glaucoma. We conducted a clinical and genetic retrospective case series to describe three cases of...

    Authors: Yun-Hsuan Lin, Nan-Kai Wang, Ling Yeung, Chi-Chun Lai and Lan-Hsin Chuang

    Citation: BMC Ophthalmology 2018 18:323

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  18. Content type: Research article

    Central corneal thickness (CCT) has long been implicated to affect glaucoma predisposition. Several reports have identified that thinner CCT is a risk factor for open-angle glaucoma, and that CCT can be very v...

    Authors: Sana’ Muhsen, Feras Alkhalaileh, Mohammad Hamdan and Saif Aldeen AlRyalat

    Citation: BMC Ophthalmology 2018 18:279

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  19. Content type: Research article

    The membrane frizzled-related protein (MFRP) gene is involved in axial length (AL) regulation and MFRP mutations cause nanophthalmos; also, the hepatocyte growth factor (HGF) gene is reported to result in morphol...

    Authors: Shaolin Wang, Wenjuan Zhuang, Jianqing Ma, Manyun Xu, Shunyu Piao, Juan Hao, Wen Zhang, Hao Chi, Zhongqi Xue and Shaoping Ha

    Citation: BMC Ophthalmology 2018 18:271

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  20. Content type: Case report

    To describe a unique case of decompression retinopathy manifesting as pre-macular subhyaloid hemorrhage that occurs in a nine-day old child after undergoing a non-penetrating deep sclerectomy for primary conge...

    Authors: Prithvi Ramtohul, Maëva Chardavoine, Marie Beylerian, Aurore Aziz, Frédéric Matonti and Danièle Denis

    Citation: BMC Ophthalmology 2018 18:240

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  21. Content type: Research article

    To evaluate differences of intraocular pressure (IOP) measurements performed with Goldmann applanation tonometer (GAT), dynamic contour tonometer (DCT), rebound tonometry (RT), Ocular Response Analyzer (ORA) a...

    Authors: Michele Lanza, Michele Rinaldi, Ugo Antonello Gironi Carnevale, Silvio di Staso, Mario Bifani Sconocchia and Ciro Costagliola

    Citation: BMC Ophthalmology 2018 18:233

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  22. Content type: Technical advance

    To describe a new technique and present its long-term outcome for prevention of Ahmed glaucoma valve (AGV) tube exposure in patients with refractory glaucoma.

    Authors: O. M. Gedar Totuk, K. Kabadayi, A. Colakoglu, N. Ekizoglu and U. Aykan

    Citation: BMC Ophthalmology 2018 18:226

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  23. Content type: Research article

    Despite the increasing emphasis on the role of glaucoma-specific patient-reported outcome measures (PROMs) as relevant outcome measures for the impact of glaucoma and its intervention on patients' daily lives,...

    Authors: Owen Kim Hee, Zheng-Xian Thng, Hong-Yuan Zhu and Ecosse Luc Lamoureux

    Citation: BMC Ophthalmology 2018 18:197

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  24. Content type: Research article

    Fixation changes in glaucoma are generally overlooked, as they are not strikingly evident as in macular diseases. Fundus perimetry might give additional insights into this aspect, along with traditional perime...

    Authors: Giovanni Montesano, David P. Crabb, Pete R. Jones, Paolo Fogagnolo, Maurizio Digiuni and Luca M. Rossetti

    Citation: BMC Ophthalmology 2018 18:191

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  25. Content type: Research article

    To investigate the prevalence of depression and anxiety among subjects with self-reported glaucoma and the association between self-reported glaucoma and depression respectively anxiety in a European cohort.

    Authors: J. Rezapour, S. Nickels, A. K. Schuster, M. Michal, T. Münzel, P. S. Wild, I. Schmidtmann, K. Lackner, A. Schulz, N. Pfeiffer and M. E. Beutel

    Citation: BMC Ophthalmology 2018 18:157

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  26. Content type: Research article

    Previous cross-sectional studies revealed a higher prevalence of depression among glaucoma patients. However, cohort studies were in lack to build the risk of incident depression after the diagnosis of glaucom...

    Authors: Yu-Yen Chen, Yun-Ju Lai, Jen-Pang Wang, Ying-Cheng Shen, Chun-Yuan Wang, Hsin-Hua Chen, Hsiao-Yun Hu and Pesus Chou

    Citation: BMC Ophthalmology 2018 18:146

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  27. Content type: Research article

    The aim of this study, which included a baseline cross-sectional study and a 3-year follow-up prospective study, was to investigate the association between glaucomatous visual field damage and driving cessatio...

    Authors: Aya Takahashi, Kenya Yuki, Sachiko Awano-Tanabe, Takeshi Ono, Daisuke Shiba and Kazuo Tsubota

    Citation: BMC Ophthalmology 2018 18:122

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  28. Content type: Research article

    To evaluate the outcomes of Viscocanalostomy (VC) and Phacoviscocanalostomy (PV) in controlling primary and secondary glaucoma in a large cohort of patients from a single eye unit and performed by a single sur...

    Authors: Andrew Want, Derek K.-H. Ho, Bhavani Karri and Divya Mathews

    Citation: BMC Ophthalmology 2018 18:111

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  29. Content type: Research article

    To report the results of the repair of conjunctival erosions resulting from glaucoma drainage device surgery using collagen-glycosaminoglycane matrices (CGM).

    Authors: André Rosentreter, Alexandra Lappas, Randolf Alexander Widder, Maged Alnawaiseh and Thomas Stefan Dietlein

    Citation: BMC Ophthalmology 2018 18:60

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  30. Content type: Research article

    Many studies have investigated the clinical benefits of Ologen for trabeculectomy. However, its benefits for Ahmed glaucoma valve (AGV) implantation have not been investigated as extensively. The aim of this s...

    Authors: Tai Jun Kim, Sohyun Kang, Jin Wook Jeoung, Young Kook Kim and Ki Ho Park

    Citation: BMC Ophthalmology 2018 18:45

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  31. Content type: Research article

    To investigate the relationship between clinical risk factors, including visual field (VF) defects and visual acuity, and a fear of falling, among patients with primary open-angle glaucoma (POAG).

    Authors: Sayaka Adachi, Kenya Yuki, Sachiko Awano-Tanabe, Takeshi Ono, Daisuke Shiba, Hiroshi Murata, Ryo Asaoka and Kazuo Tsubota

    Citation: BMC Ophthalmology 2018 18:39

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  32. Content type: Research article

    Trabecular meshwork (TM) plays an important role in maintaining normal intraocular pressure (IOP). Studies have shown that glaucomatous TM tissues are stiffer than those of normal tissue. The high expression o...

    Authors: Chuan Wang, Lin Li and Zhicheng Liu

    Citation: BMC Ophthalmology 2017 17:268

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  33. Content type: Research article

    Glaucoma is a chronic disease characterized by irreversible optic nerve damage and visual field loss that leads to visual impairment and blindness; ultimately limiting personal independence and compromising ov...

    Authors: Fisseha A. Ayele, Banchamelak Zeraye, Yared Assefa, Kbrom Legesse, Telake Azale and Matthew J. Burton

    Citation: BMC Ophthalmology 2017 17:248

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