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Section edited by Luca Rossetti

This section takes submissions looking at all aspects of the prevention, diagnosis and management of glaucoma. The section also welcomes basic science studies including molecular and cellular biology, genetics, pathophysiology and epidemiology. Prospective clinical studies, especially randomized controlled trials are encouraged.

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  1. Content type: Research article

    Central corneal thickness (CCT) has long been implicated to affect glaucoma predisposition. Several reports have identified that thinner CCT is a risk factor for open-angle glaucoma, and that CCT can be very v...

    Authors: Sana’ Muhsen, Feras Alkhalaileh, Mohammad Hamdan and Saif Aldeen AlRyalat

    Citation: BMC Ophthalmology 2018 18:279

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  2. Content type: Research article

    The membrane frizzled-related protein (MFRP) gene is involved in axial length (AL) regulation and MFRP mutations cause nanophthalmos; also, the hepatocyte growth factor (HGF) gene is reported to result in morphol...

    Authors: Shaolin Wang, Wenjuan Zhuang, Jianqing Ma, Manyun Xu, Shunyu Piao, Juan Hao, Wen Zhang, Hao Chi, Zhongqi Xue and Shaoping Ha

    Citation: BMC Ophthalmology 2018 18:271

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  3. Content type: Case report

    To describe a unique case of decompression retinopathy manifesting as pre-macular subhyaloid hemorrhage that occurs in a nine-day old child after undergoing a non-penetrating deep sclerectomy for primary conge...

    Authors: Prithvi Ramtohul, Maëva Chardavoine, Marie Beylerian, Aurore Aziz, Frédéric Matonti and Danièle Denis

    Citation: BMC Ophthalmology 2018 18:240

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  4. Content type: Research article

    To evaluate differences of intraocular pressure (IOP) measurements performed with Goldmann applanation tonometer (GAT), dynamic contour tonometer (DCT), rebound tonometry (RT), Ocular Response Analyzer (ORA) a...

    Authors: Michele Lanza, Michele Rinaldi, Ugo Antonello Gironi Carnevale, Silvio di Staso, Mario Bifani Sconocchia and Ciro Costagliola

    Citation: BMC Ophthalmology 2018 18:233

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  5. Content type: Technical advance

    To describe a new technique and present its long-term outcome for prevention of Ahmed glaucoma valve (AGV) tube exposure in patients with refractory glaucoma.

    Authors: O. M. Gedar Totuk, K. Kabadayi, A. Colakoglu, N. Ekizoglu and U. Aykan

    Citation: BMC Ophthalmology 2018 18:226

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  6. Content type: Research article

    Despite the increasing emphasis on the role of glaucoma-specific patient-reported outcome measures (PROMs) as relevant outcome measures for the impact of glaucoma and its intervention on patients' daily lives,...

    Authors: Owen Kim Hee, Zheng-Xian Thng, Hong-Yuan Zhu and Ecosse Luc Lamoureux

    Citation: BMC Ophthalmology 2018 18:197

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  7. Content type: Research article

    Fixation changes in glaucoma are generally overlooked, as they are not strikingly evident as in macular diseases. Fundus perimetry might give additional insights into this aspect, along with traditional perime...

    Authors: Giovanni Montesano, David P. Crabb, Pete R. Jones, Paolo Fogagnolo, Maurizio Digiuni and Luca M. Rossetti

    Citation: BMC Ophthalmology 2018 18:191

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  8. Content type: Research article

    To investigate the prevalence of depression and anxiety among subjects with self-reported glaucoma and the association between self-reported glaucoma and depression respectively anxiety in a European cohort.

    Authors: J. Rezapour, S. Nickels, A. K. Schuster, M. Michal, T. Münzel, P. S. Wild, I. Schmidtmann, K. Lackner, A. Schulz, N. Pfeiffer and M. E. Beutel

    Citation: BMC Ophthalmology 2018 18:157

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  9. Content type: Research article

    Previous cross-sectional studies revealed a higher prevalence of depression among glaucoma patients. However, cohort studies were in lack to build the risk of incident depression after the diagnosis of glaucom...

    Authors: Yu-Yen Chen, Yun-Ju Lai, Jen-Pang Wang, Ying-Cheng Shen, Chun-Yuan Wang, Hsin-Hua Chen, Hsiao-Yun Hu and Pesus Chou

    Citation: BMC Ophthalmology 2018 18:146

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  10. Content type: Research article

    The aim of this study, which included a baseline cross-sectional study and a 3-year follow-up prospective study, was to investigate the association between glaucomatous visual field damage and driving cessatio...

    Authors: Aya Takahashi, Kenya Yuki, Sachiko Awano-Tanabe, Takeshi Ono, Daisuke Shiba and Kazuo Tsubota

    Citation: BMC Ophthalmology 2018 18:122

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  11. Content type: Research article

    To evaluate the outcomes of Viscocanalostomy (VC) and Phacoviscocanalostomy (PV) in controlling primary and secondary glaucoma in a large cohort of patients from a single eye unit and performed by a single sur...

    Authors: Andrew Want, Derek K.-H. Ho, Bhavani Karri and Divya Mathews

    Citation: BMC Ophthalmology 2018 18:111

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  12. Content type: Research article

    To report the results of the repair of conjunctival erosions resulting from glaucoma drainage device surgery using collagen-glycosaminoglycane matrices (CGM).

    Authors: André Rosentreter, Alexandra Lappas, Randolf Alexander Widder, Maged Alnawaiseh and Thomas Stefan Dietlein

    Citation: BMC Ophthalmology 2018 18:60

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  13. Content type: Research article

    Many studies have investigated the clinical benefits of Ologen for trabeculectomy. However, its benefits for Ahmed glaucoma valve (AGV) implantation have not been investigated as extensively. The aim of this s...

    Authors: Tai Jun Kim, Sohyun Kang, Jin Wook Jeoung, Young Kook Kim and Ki Ho Park

    Citation: BMC Ophthalmology 2018 18:45

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  14. Content type: Research article

    To investigate the relationship between clinical risk factors, including visual field (VF) defects and visual acuity, and a fear of falling, among patients with primary open-angle glaucoma (POAG).

    Authors: Sayaka Adachi, Kenya Yuki, Sachiko Awano-Tanabe, Takeshi Ono, Daisuke Shiba, Hiroshi Murata, Ryo Asaoka and Kazuo Tsubota

    Citation: BMC Ophthalmology 2018 18:39

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  15. Content type: Research article

    Trabecular meshwork (TM) plays an important role in maintaining normal intraocular pressure (IOP). Studies have shown that glaucomatous TM tissues are stiffer than those of normal tissue. The high expression o...

    Authors: Chuan Wang, Lin Li and Zhicheng Liu

    Citation: BMC Ophthalmology 2017 17:268

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  16. Content type: Research article

    Glaucoma is a chronic disease characterized by irreversible optic nerve damage and visual field loss that leads to visual impairment and blindness; ultimately limiting personal independence and compromising ov...

    Authors: Fisseha A. Ayele, Banchamelak Zeraye, Yared Assefa, Kbrom Legesse, Telake Azale and Matthew J. Burton

    Citation: BMC Ophthalmology 2017 17:248

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  17. Content type: Research article

    Previous studies have associated the Interleukin-1 (IL-1) gene clusters polymorphisms with the risk of primary open-angle glaucoma (POAG). However, the results were not consistent. Here, we performed a meta-analy...

    Authors: Junhua Li, Yifan Feng, Mi Sun Sung, Tae Hee Lee and Sang Woo Park

    Citation: BMC Ophthalmology 2017 17:218

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  18. Content type: Research article

    Goldmann applanation tonometry (GAT) error relative to intracameral intraocular pressure (IOP) has not been examined comparatively in both human cadaver eyes and in live human eyes. Futhermore, correlations to...

    Authors: Sean McCafferty, Jason Levine, Jim Schwiegerling and Eniko T. Enikov

    Citation: BMC Ophthalmology 2017 17:215

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  19. Content type: Research article

    The objective of this study was to evaluate the efficacy of Viscocanalostomy/Phacoviscocanalostomy (VC/PVC) in lowering intraocular pressure (IOP) in Normal Tension Glaucoma (NTG) patients.

    Authors: Derek Kwun-hong Ho, Adesuwa Garrick, Seemeen Aazem and Divya Mathews

    Citation: BMC Ophthalmology 2017 17:201

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  20. Content type: Research article

    To compare the measurement of intraocular pressure (IOP) among the three different non-contact tonometers (NCT) and the Goldmann applanation tonometer (GAT) for non-glaucomatous subjects.

    Authors: Seung Pil Bang, Chong Eun Lee and Yu Cheol Kim

    Citation: BMC Ophthalmology 2017 17:199

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  21. Content type: Research article

    Surgeries are inevitable for treating primary congenital glaucoma (PCG) and risk factors of surgical failure play a key role in surgical decision making. The aim of this study was to investigate the influence ...

    Authors: Chunyu Guo, Yue Wu, Li Xu, Mao Li, Zi Wang, Ni Ni and Wenyi Guo

    Citation: BMC Ophthalmology 2017 17:170

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  22. Content type: Research article

    Raising public awareness and knowledge about glaucoma is a key for early case identification and prevention of blindness. However, awareness and knowledge about glaucoma is unknown at community level, making p...

    Authors: Destaye Shiferaw Alemu, Alemayehu Desalegn Gudeta and Kbrom Legesse Gebreselassie

    Citation: BMC Ophthalmology 2017 17:154

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  23. Content type: Research article

    Glaucoma is one of the most leading causes of permanent visual impairments in Korea, and social expenses spent for the glaucoma are increasing. This study is to identify association between socioeconomic statu...

    Authors: Haejune Sung, Hyun Ho Shin, Yunseng Baek, Gyu Ah Kim, Jae Sang Koh, Eun-Cheol Park and Jaeyong Shin

    Citation: BMC Ophthalmology 2017 17:153

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  24. Content type: Research article

    The effects of preservatives of antiglaucoma medications on corneal surface and tear function have been widely shown in literature; it’s not the same as regards the active compounds themselves. The purpose of ...

    Authors: Teresa Rolle, Roberta Spinetta and Raffaele Nuzzi

    Citation: BMC Ophthalmology 2017 17:136

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  25. Content type: Research article

    The purpose of this study was to compare the diagnostic performance of isolated-check visual evoked potential (icVEP) with that of retinal ganglion cell-inner plexiform layer (GCILP) analysis using optical coh...

    Authors: XiangWu Chen and YingXi Zhao

    Citation: BMC Ophthalmology 2017 17:77

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  26. Content type: Research article

    The aim of this work is to evaluate efficacy and tolerability of preservative containing 0.0015% tafluprost and preservative-free 0.0015% tafluprost using a prospective crossover study.

    Authors: Wonseok Lee, Sunghoon Lee, HyoungWon Bae, Chan Yun Kim and Gong Je Seong

    Citation: BMC Ophthalmology 2017 17:61

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  27. Content type: Research article

    To compare the lamina cribrosa between eyes with and without neovascular glaucoma (NVG) using enhanced depth imaging spectral-domain optical coherence tomography.

    Authors: Satoshi Yokota, Yuji Takihara, Yoshihiro Takamura and Masaru Inatani

    Citation: BMC Ophthalmology 2017 17:57

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  28. Content type: Research article

    Matrix metalloproteinases (MMPs) polymorphisms have been implicated in the pathogenesis of glaucoma risk. However, the results were controversial. We performed a meta-analysis to evaluate the precise associati...

    Authors: Ming-Yue Wu, Yang Wu, Yong Zhang, Cai-Yun Liu, Chun-Yan Deng, Le Peng and Lan Zhou

    Citation: BMC Ophthalmology 2017 17:48

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  29. Content type: Research article

    In Posner-Schlossman syndrome (PSS), which is characterized by recurrent unilateral attacks of ocular hypertension. Surgical treatment is sometimes necessary because intraocular pressure (IOP) cannot be contro...

    Authors: Kazuichi Maruyama, Yuko Maruyama, Sunao Sugita, Kazuhiko Mori, Yu Yokoyama, Shiho Sanuki-Kunimatsu, Hiroko Nakagawa, Shigeru Kinoshita, Manabu Mochizuki and Toru Nakazawa

    Citation: BMC Ophthalmology 2017 17:45

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  30. Content type: Research article

    To determine the influences of myopia and optic disc size on ganglion cell-inner plexiform layer (GCIPL) and peripapillary retinal nerve fiber layer (RNFL) thickness profiles obtained by spectral domain optica...

    Authors: Sam Seo, Chong Eun Lee, Jae Hoon Jeong, Ki Ho Park, Dong Myung Kim and Jin Wook Jeoung

    Citation: BMC Ophthalmology 2017 17:22

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  31. Content type: Research article

    Oxidative stress contributes to both intraocular pressure regulation and glaucomatous neuropathy. The systemic redox status (solitary determination) was examined in primary open-angle glaucoma (POAG) patients ...

    Authors: Wojciech Rokicki, Jolanta Zalejska-Fiolka, Dorota Pojda-Wilczek, Alicja Hampel, Wojciech Majewski, Serap Ogultekin and Ewa Mrukwa-Kominek

    Citation: BMC Ophthalmology 2017 17:13

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  32. Content type: Research article

    To analyze the most common neurophthalmological conditions that may mimic glaucomatous optic neuropathy and to determine which most often lead to misdiagnosis when evaluated by a glaucoma specialist.

    Authors: Diego Torres Dias, Michele Ushida, Roberto Battistella, Syril Dorairaj and Tiago Santos Prata

    Citation: BMC Ophthalmology 2017 17:2

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  33. Content type: Research article

    To compare corneal hysteresis (CH) measurements between patients with glaucoma, ocular hypertension (OHT) and glaucoma-like optic discs (GLD)- defined as a cup to disc ratio greater than or equal to 0.6 with n...

    Authors: Melissa L. Murphy, Olya Pokrovskaya, Marie Galligan and Colm O’Brien

    Citation: BMC Ophthalmology 2017 17:1

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