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Section edited by Luca Rossetti

This section takes submissions looking at all aspects of the prevention, diagnosis and management of glaucoma. The section also welcomes basic science studies including molecular and cellular biology, genetics, pathophysiology and epidemiology. Prospective clinical studies, especially randomized controlled trials are encouraged.

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  1. Content type: Case report

    The subconjunctival anesthesia with local anesthetics is considered as a low-risk procedure allowing ocular surgery without serious complications typical for retro- or parabulbar anesthesia, especially in pati...

    Authors: Katharina Knoll, Kristine Chobanyan-Jürgens, Dirk O. Stichtenoth, Ingo Roland Volkmann, Katerina Hufendiek and Carsten Framme

    Citation: BMC Ophthalmology 2019 19:195

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  2. Content type: Research article

    A patient’s perception of how their glaucoma is managed will influence both adherence to their medication and outcome measures such as quality of life.

    Authors: Alison Fraenkel, Graham A. Lee, Stephen J Vincent, Roslyn A. Vincent, Rupert R. A. Bourne and Peter Shah

    Citation: BMC Ophthalmology 2019 19:192

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  3. Content type: Research article

    The object of this study is to investigate the effect of early bleb parameters measured by three-dimensional anterior-segment optical coherence tomography on the surgical success of trabeculectomy.

    Authors: Utako Tsutsumi-Kuroda, Sachi Kojima, Ayako Fukushima, Kei-Ichi Nakashima, Keiichiro Iwao, Hidenobu Tanihara and Toshihiro Inoue

    Citation: BMC Ophthalmology 2019 19:155

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  4. Content type: Case report

    Interface fluid syndrome (IFS) is an unusual complication after laser-assisted in-situ keratomileusis (LASIK). We report the first case of IFS after uncomplicated phacotrabeculectomy in a patient who had under...

    Authors: Chung Young Kim, Young Ho Jung, Eun Ji Lee, Joon Young Hyon, Kyu Hyung Park and Tae Woo Kim

    Citation: BMC Ophthalmology 2019 19:74

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  5. Content type: Research article

    Diabetic macular edema (DME) can be treated with different alternatives, among them Dexamethasone intravitreal implant 0.7 mg (DEX 0.7) has demonstrated that may improve both central macular thickness (CMT) an...

    Authors: Verónica Castro-Navarro, Enrique Cervera-Taulet, Catalina Navarro-Palop, Clara Monferrer-Adsuara, Laura Hernández-Bel and Javier Montero-Hernández

    Citation: BMC Ophthalmology 2019 19:15

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  6. Content type: Research article

    Central corneal thickness (CCT) has long been implicated to affect glaucoma predisposition. Several reports have identified that thinner CCT is a risk factor for open-angle glaucoma, and that CCT can be very v...

    Authors: Sana’ Muhsen, Feras Alkhalaileh, Mohammad Hamdan and Saif Aldeen AlRyalat

    Citation: BMC Ophthalmology 2018 18:279

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  7. Content type: Case report

    To describe a unique case of decompression retinopathy manifesting as pre-macular subhyaloid hemorrhage that occurs in a nine-day old child after undergoing a non-penetrating deep sclerectomy for primary conge...

    Authors: Prithvi Ramtohul, Maëva Chardavoine, Marie Beylerian, Aurore Aziz, Frédéric Matonti and Danièle Denis

    Citation: BMC Ophthalmology 2018 18:240

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  8. Content type: Technical advance

    To describe a new technique and present its long-term outcome for prevention of Ahmed glaucoma valve (AGV) tube exposure in patients with refractory glaucoma.

    Authors: O. M. Gedar Totuk, K. Kabadayi, A. Colakoglu, N. Ekizoglu and U. Aykan

    Citation: BMC Ophthalmology 2018 18:226

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  9. Content type: Research article

    To investigate the prevalence of depression and anxiety among subjects with self-reported glaucoma and the association between self-reported glaucoma and depression respectively anxiety in a European cohort.

    Authors: J. Rezapour, S. Nickels, A. K. Schuster, M. Michal, T. Münzel, P. S. Wild, I. Schmidtmann, K. Lackner, A. Schulz, N. Pfeiffer and M. E. Beutel

    Citation: BMC Ophthalmology 2018 18:157

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  10. Content type: Research article

    The aim of this study, which included a baseline cross-sectional study and a 3-year follow-up prospective study, was to investigate the association between glaucomatous visual field damage and driving cessatio...

    Authors: Aya Takahashi, Kenya Yuki, Sachiko Awano-Tanabe, Takeshi Ono, Daisuke Shiba and Kazuo Tsubota

    Citation: BMC Ophthalmology 2018 18:122

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  11. Content type: Research article

    Many studies have investigated the clinical benefits of Ologen for trabeculectomy. However, its benefits for Ahmed glaucoma valve (AGV) implantation have not been investigated as extensively. The aim of this s...

    Authors: Tai Jun Kim, Sohyun Kang, Jin Wook Jeoung, Young Kook Kim and Ki Ho Park

    Citation: BMC Ophthalmology 2018 18:45

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  12. Content type: Research article

    Glaucoma is a chronic disease characterized by irreversible optic nerve damage and visual field loss that leads to visual impairment and blindness; ultimately limiting personal independence and compromising ov...

    Authors: Fisseha A. Ayele, Banchamelak Zeraye, Yared Assefa, Kbrom Legesse, Telake Azale and Matthew J. Burton

    Citation: BMC Ophthalmology 2017 17:248

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  13. Content type: Research article

    Surgeries are inevitable for treating primary congenital glaucoma (PCG) and risk factors of surgical failure play a key role in surgical decision making. The aim of this study was to investigate the influence ...

    Authors: Chunyu Guo, Yue Wu, Li Xu, Mao Li, Zi Wang, Ni Ni and Wenyi Guo

    Citation: BMC Ophthalmology 2017 17:170

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  14. Content type: Research article

    Raising public awareness and knowledge about glaucoma is a key for early case identification and prevention of blindness. However, awareness and knowledge about glaucoma is unknown at community level, making p...

    Authors: Destaye Shiferaw Alemu, Alemayehu Desalegn Gudeta and Kbrom Legesse Gebreselassie

    Citation: BMC Ophthalmology 2017 17:154

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  15. Content type: Research article

    The purpose of this study was to compare the diagnostic performance of isolated-check visual evoked potential (icVEP) with that of retinal ganglion cell-inner plexiform layer (GCILP) analysis using optical coh...

    Authors: XiangWu Chen and YingXi Zhao

    Citation: BMC Ophthalmology 2017 17:77

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  16. Content type: Research article

    To compare the lamina cribrosa between eyes with and without neovascular glaucoma (NVG) using enhanced depth imaging spectral-domain optical coherence tomography.

    Authors: Satoshi Yokota, Yuji Takihara, Yoshihiro Takamura and Masaru Inatani

    Citation: BMC Ophthalmology 2017 17:57

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  17. Content type: Research article

    In Posner-Schlossman syndrome (PSS), which is characterized by recurrent unilateral attacks of ocular hypertension. Surgical treatment is sometimes necessary because intraocular pressure (IOP) cannot be contro...

    Authors: Kazuichi Maruyama, Yuko Maruyama, Sunao Sugita, Kazuhiko Mori, Yu Yokoyama, Shiho Sanuki-Kunimatsu, Hiroko Nakagawa, Shigeru Kinoshita, Manabu Mochizuki and Toru Nakazawa

    Citation: BMC Ophthalmology 2017 17:45

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  18. Content type: Research article

    To determine the influences of myopia and optic disc size on ganglion cell-inner plexiform layer (GCIPL) and peripapillary retinal nerve fiber layer (RNFL) thickness profiles obtained by spectral domain optica...

    Authors: Sam Seo, Chong Eun Lee, Jae Hoon Jeong, Ki Ho Park, Dong Myung Kim and Jin Wook Jeoung

    Citation: BMC Ophthalmology 2017 17:22

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  19. Content type: Research article

    Oxidative stress contributes to both intraocular pressure regulation and glaucomatous neuropathy. The systemic redox status (solitary determination) was examined in primary open-angle glaucoma (POAG) patients ...

    Authors: Wojciech Rokicki, Jolanta Zalejska-Fiolka, Dorota Pojda-Wilczek, Alicja Hampel, Wojciech Majewski, Serap Ogultekin and Ewa Mrukwa-Kominek

    Citation: BMC Ophthalmology 2017 17:13

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  20. Content type: Research article

    To analyze the most common neurophthalmological conditions that may mimic glaucomatous optic neuropathy and to determine which most often lead to misdiagnosis when evaluated by a glaucoma specialist.

    Authors: Diego Torres Dias, Michele Ushida, Roberto Battistella, Syril Dorairaj and Tiago Santos Prata

    Citation: BMC Ophthalmology 2017 17:2

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  21. Content type: Research article

    To compare corneal hysteresis (CH) measurements between patients with glaucoma, ocular hypertension (OHT) and glaucoma-like optic discs (GLD)- defined as a cup to disc ratio greater than or equal to 0.6 with n...

    Authors: Melissa L. Murphy, Olya Pokrovskaya, Marie Galligan and Colm O’Brien

    Citation: BMC Ophthalmology 2017 17:1

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  22. Content type: Research article

    Antifibrotic agents are commonly utilized to enhance the success rates of trabeculectomy. Novel approaches to further improve success rates and reduce the risks of complications are needed. The purpose of this...

    Authors: Angelo P. Tanna, Alfred W. Rademaker, C. Gustavo de Moraes, David G. Godfrey, Steven R. Sarkisian Jr., Steven D. Vold and Robert Ritch

    Citation: BMC Ophthalmology 2016 16:217

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  23. Content type: Research article

    To identify success predictors and to study the role of the fellow untreated eye as a co-variable for adjustment of intraocular pressure (IOP) outcomes following selective laser trabeculoplasty (SLT) in early ...

    Authors: Mikael Chun, Carolina P. B. Gracitelli, Flavio S. Lopes, Luis G. Biteli, Michele Ushida and Tiago S. Prata

    Citation: BMC Ophthalmology 2016 16:206

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  24. Content type: Research article

    Although glaucoma is the lead cause of irreversible blindness globally, the condition shows no signs or symptoms until later stages. Knowledge about the disease is known to influence utilization of eye screeni...

    Authors: Virtue Fiawokome De-Gaulle and Phyllis Dako-Gyeke

    Citation: BMC Ophthalmology 2016 16:204

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  25. Content type: Research article

    In randomized, controlled trials of open-angle glaucoma (OAG) or ocular hypertension (OHT), bimatoprost 0.01 % improved tolerability while retaining the intraocular pressure (IOP)-lowering efficacy of bimatopr...

    Authors: Ying Ying Chen, Tsing-Hong Wang, Catherine Liu, Kwou-Yeung Wu, Shin-Lin Chiu, Susan Simonyi and Da-Wen Lu

    Citation: BMC Ophthalmology 2016 16:162

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  26. Content type: Research article

    Methylenetetrahydrofolate reductase (MTHFR), a critical enzyme in folate metabolism is involved in DNA synthesis, DNA repair and DNA methylation. The functional polymorphism of MTHFR gene, C677T has been shown to...

    Authors: Hamoud Al-Shahrani, Najwa Al-Dabbagh, Nourah Al-Dohayan, Misbahul Arfin, Mohammad Al-Asmari, Sadaf Rizvi and Abdulrahman Al-Asmari

    Citation: BMC Ophthalmology 2016 16:156

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  27. Content type: Case report

    Iridocorneal endothelial (ICE) syndrome occurs mainly in young and middle-aged women and typically presents as a unilateral disease characterized by abnormalities of the iris and corneal endothelium. While the...

    Authors: Keita Suzuki, Tadashi Mizuguchi, Yui Seno, Atsuhiro Tanikawa and Masayuki Horiguchi

    Citation: BMC Ophthalmology 2016 16:155

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  28. Content type: Research article

    To present a comprehensive approach for the management of patients with neovascular glaucoma (NVG) aiming to preserve visual function and complement pan-retinal photocoagulation (PRP) by anti-vascular endothel...

    Authors: Yaoyao Sun, Yong Liang, Peng Zhou, Huijuan Wu, Xianru Hou, Zeqin Ren, Xiaoxin Li and Mingwei Zhao

    Citation: BMC Ophthalmology 2016 16:150

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  29. Content type: Research article

    Exercise reduces intraocular pressure (IOP) in the short term. However, it is not known whether exercise contributes to slower glaucomatous visual field defect progression.

    Authors: Satoshi Yokota, Yuji Takihara, Kanako Kimura, Yoshihiro Takamura and Masaru Inatani

    Citation: BMC Ophthalmology 2016 16:147

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  30. Content type: Research article

    To evaluate the short-term reproducibility of diurnal intraocular pressure (IOP) and ocular perfusion pressure (OPP) measurements in normal volunteers, untreated normal-tension glaucoma (NTG) and primary open-...

    Authors: Yanlin Gao, Bing Wan, Peiyu Li, Yan Zhang and Xin Tang

    Citation: BMC Ophthalmology 2016 16:145

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  31. Content type: Case report

    The parapapillary gamma zone has recently been defined as the parapapillary region free of Bruch’s membrane. Although it has been reported the presence of defects in peripapillary gamma zone, hitherto undescri...

    Authors: Xinxin Hu, Yi Dai, Jost Jonas and Xinghuai Sun

    Citation: BMC Ophthalmology 2016 16:143

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  32. Content type: Research article

    Patient education materials should be written at a level that is understandable for patients with low health literacy. The aims of this study are (1) to review the literature on readability of ophthalmic patie...

    Authors: Andrew M. Williams, Kelly W. Muir and Jullia A. Rosdahl

    Citation: BMC Ophthalmology 2016 16:133

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  33. Content type: Research article

    Good adherence to ocular hypotensive agents is important to control intraocular pressure and hence to prevent progressive glaucomatous optic nerve head damage. Periodic investigation of adherence is crucial in...

    Authors: Tesfay Mehari, Abeba T. Giorgis and Workineh Shibeshi

    Citation: BMC Ophthalmology 2016 16:131

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